Results 81 to 90 of about 65,722 (350)
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Phrenic-specific transcriptional programs shape respiratory motor output
eLife, 2020 The precise pattern of motor neuron (MN) activation is essential for the execution of motor actions; however, the molecular mechanisms that give rise to specific patterns of MN activity are largely unknown.
Alicia N Vagnozzi +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Circulating cell adhesion molecules in systemic sclerosis: a systematic review and meta-analysis
Frontiers in ImmunologyIntroductionPatients with systemic sclerosis (SSc) have an increased risk of endothelial dysfunction, atherosclerosis, and cardiovascular events compared to the general population.
Arduino A. Mangoni +2 more
doaj +1 more source
Leptospira interrogans binds to cadherins. [PDF]
PLoS Neglected Tropical Diseases, 2014 Leptospirosis, caused by pathogenic species of Leptospira, is the most widespread zoonosis and has emerged as a major public health problem worldwide. The adhesion of pathogenic Leptospira to host cells, and to extracellular matrix (ECM) components, is ...
Karen Evangelista +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
Fluidization and Active Thinning by Molecular Kinetics in Active Gels
, 2017 We derive the constitutive equations of an active polar gel from a model for the dynamics of elastic molecules that link polar elements. Molecular binding kinetics induces the fluidization of the material, giving rise to Maxwell viscoelasticity and ...
Alert, Ricard +2 more
core +1 more source
Advanced Functional Materials, EarlyView.Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi +5 more
wiley +1 more source
CDH13 (cadherin 13, H-cadherin (heart)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on CDH13 (cadherin 13, H-cadherin (heart)), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire +2 more sources
Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes [PDF]
, 2003 Background - Further to promoting angiogenesis, cell therapy may be an approach for cardiac regeneration. Recent studies suggest that progenitor cells can transdifferentiate into other lineages. However, the transdifferentiation potential of endothelial
Aicher, A +9 more
core +1 more source