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Advances in astrocytic calcium signaling research [PDF]

Frontiers in Cellular Neuroscience
Astrocytes are the most abundant glial cells in the central nervous system. They detect neuronal activity through Ca2+ signals and thereby regulate synaptic plasticity, integrate neuronal information, and maintain extracellular homeostasis.
Yuzhu Chen, Yejun Ye, Joyce Jia, Binhao Long, Tingting Dou, Xingke Yan   +5 more
doaj   +2 more sources

Remodeling of calcium signaling and store operated calcium entry as a consequence of human neural progenitor cell differentiation [PDF]

Scientific Reports
The differentiation of neural progenitor cells into glial and neuronal lineages is a fundamental process in neurodevelopment. This complex process is tightly regulated by several signaling pathways, including calcium signaling. Calcium signaling not only
Silke B. Chalmers, Mélanie Robitaille, Francisco Sadras, Sarah J. Roberts-Thomson, Gregory R. Monteith   +4 more
doaj   +2 more sources

Correction: Advances in astrocytic calcium signaling research [PDF]

Frontiers in Cellular Neuroscience
Yuzhu Chen, Yejun Ye, Joyce Jia, Binhao Long, Tingting Dou, Xingke Yan   +5 more
doaj   +2 more sources

Store Operated Calcium Entry in Cell Migration and Cancer Metastasis

Cells, 2021
Ca2+ signaling is ubiquitous in eukaryotic cells and modulates many cellular events including cell migration. Directional cell migration requires the polarization of both signaling and structural elements.
Ayat S. Hammad, Khaled Machaca
doaj   +1 more source

Correction: Abrogation of store-operated Ca2+ entry protects against crystal-induced ER stress in human proximal tubular cells

Cell Death Discovery, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41420-021-00445 ...
Farai C. Gombedza, Samuel Shin, Yianni L. Kanaras, Bidhan C. Bandyopadhyay   +3 more
doaj   +1 more source

Hypercalciuria switches Ca2+ signaling in proximal tubular cells, induces oxidative damage to promote calcium nephrolithiasis

Genes and Diseases, 2022
Proximal tubule (PT) transports most of the renal Ca2+, which was usually described as paracellular (passive). We found a regulated Ca2+ entry pathway in PT cells via the apical transient receptor potential canonical 3 (TRPC3) channel, which initiates ...
Samuel Shin, Cliff-Lawrence Ibeh, Eugenia Awuah Boadi, Bok-Eum Choi, Sanjit K. Roy, Bidhan C. Bandyopadhyay   +5 more
doaj   +1 more source

Ablation of TRPC3 disrupts Ca2+ signaling in salivary ductal cells and promotes sialolithiasis

Scientific Reports, 2023
Clinical studies and structural analyses of salivary stones strongly suggest a linkage between higher saliva calcium (Ca2+) and salivary stone formation, sialolithiasis; however, the process and the mechanism leading to Ca2+ overload during ...
Bok-Eum Choi, Samuel Shin, Sade Evans, Brij B. Singh, Bidhan C. Bandyopadhyay   +4 more
doaj   +1 more source

Titanium Dioxide Promotes the Growth and Aggregation of Calcium Phosphate and Monosodium Urate Mixed Crystals

Crystals, 2023
The increased utilization of titanium dioxide (TiO2) nanoparticles (TNPs) in various industrial and consumer products has raised concerns regarding its harmful effect due to its accumulation within the different systems of the human body.
Onyebuchi C. Ukaeje, Bidhan C. Bandyopadhyay   +1 more
doaj   +1 more source

Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia

Frontiers in Cell and Developmental Biology, 2020
In stroke and other neurological diseases, Transient Receptor Potential Melastatin 4 (TRPM4) has been reported to cause oncotic cell death which is due to an excessive influx of sodium ions.
Shunhui Wei, See Wee Low, Charlene Priscilla Poore, Bo Chen, Yahui Gao, Bernd Nilius, Ping Liao, Ping Liao, Ping Liao   +8 more
doaj   +1 more source

NAADP Signaling: New Kids on the Block

Cells, 2022
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a universal Ca2+ mobilizing second messenger essential for initiation of Ca2+ signaling. Recently, novel molecular mechanisms of both its rapid formation upon receptor stimulation and its mode of ...
Andreas H. Guse
doaj   +1 more source