Results 1 to 10 of about 149 (148)
Calcium signaling in neurodegeneration [PDF]
Molecular Neurodegeneration, 2009 Calcium is a key signaling ion involved in many different intracellular and extracellular processes ranging from synaptic activity to cell-cell communication and adhesion. The exact definition at the molecular level of the versatility of this ion has made overwhelming progress in the past several years and has been extensively reviewed.
Ute Dreses-Werringloer +3 more
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CCN3 and calcium signaling [PDF]
Cell Communication and Signaling, 2003 The CCN family of genes consists presently of six members in human (CCN1-6) also known as Cyr61 (Cystein rich 61), CTGF (Connective Tissue Growth Factor), NOV (Nephroblastoma Overexpressed gene), WISP-1, 2 and 3 (Wnt-1 Induced Secreted Proteins). Results obtained over the past decade have indicated that CCN proteins are matricellular proteins, which ...
Chang Long Li +4 more
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Calcium Signaling and Cytotoxicity [PDF]
Environmental Health Perspectives, 1999 The divalent calcium cation Ca(2+) is used as a major signaling molecule during cell signal transduction to regulate energy output, cellular metabolism, and phenotype. The basis to the signaling role of Ca(2+) is an intricate network of cellular channels and transporters that allow a low resting concentration of Ca(2+) in the cytosol of the cell ([Ca(2+
George E.N. Kass, Sten Orrenius
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Cell, 1995 Calcium ions (Ca(2+)) impact nearly every aspect of cellular life. This review examines the principles of Ca(2+) signaling, from changes in protein conformations driven by Ca(2+) to the mechanisms that control Ca(2+) levels in the cytoplasm and organelles.
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Calcium Signalling: Calcium Goes Global [PDF]
Current Biology, 2002 Recent evidence suggests that multiple calcium-releasing messengers might be activated simultaneously to regulate patterns of intracellular calcium signalling. In this way, agonists might use different messenger cocktails to encode specific signals and target selected processes.
Genazzani, Armando A., Thorn, Peter
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Calcium Signaling and Neurodegeneration [PDF]
Acta Naturae, 2010 Neurodegenerative disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and spinocerebellar ataxias (SCA) are very important both for fundamental science and for practical medicine. Despite extensive research into the causes of these diseases, clinical researchers have had
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Calcium Signalling in Pericytes [PDF]
Journal of Vascular Research, 2014 Recent advances in pericyte research have contributed to our understanding of the physiology and pathophysiology of microvessels. The microvasculature consists of arteriolar and venular networks located upstream and downstream of the capillaries.
Theodor Burdyga, Lyudmyla Borysova
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Calcium signaling in osteoclasts
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011 It has long been known that many bone diseases, including osteoporosis, involve abnormalities in osteoclastic bone resorption. As a result, there has been intense study of the mechanisms that regulate both the differentiation and bone resorbing function of osteoclast cells.
James W. Putney, Sung-Yong Hwang
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Neuronal Calcium Signaling [PDF]
Neuron, 1998 I would like to thank Martin Bootman for preparing the figures. This work was supported by a grant from the European Commission BIOMED2 (BMH4-CT96-0656).
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Calcium signalling in T cells [PDF]
Nature Reviews Immunology, 2019 Calcium (Ca2+) signalling is of paramount importance to immunity. Regulated increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex and crucial effector functions such as metabolism, proliferation, differentiation, antibody and cytokine secretion and cytotoxicity.
Mohamed Trebak, Jean-Pierre Kinet
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