Genome-wide CRISPR screening identifies Annexin A1 as a facilitator of porcine astrovirus entry. [PDF]
Luo Y +12 more
europepmc +1 more source
Micro/Nanorobot for Drug Delivery—A Review of Material Selections
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley +1 more source
Methodological validation of a cryo-TEM-based detection method for empty capsid ratio in recombinant adeno-associated virus. [PDF]
Xu L +11 more
europepmc +1 more source
Graphical Abstract and Lay Summary A recombinant adenovirus type 5–based vaccine encoding the full‐length SARS‐CoV‐2 Spike glycoprotein (Ad5Spike) was evaluated for its ability to induce cellular and humoral immune responses in BALB/c mice. Immunization with Ad5Spike resulted in the generation of antigen‐specific cellular immunity, characterized by ...
Fulya Erendor +2 more
wiley +1 more source
<i>Atkinsonella hypoxylon</i> virus capsid structure highlights the diversity of capsid proteins among the <i>Partitiviridae</i>. [PDF]
Venturi M +5 more
europepmc +1 more source
Theoretical Insights Into the Viral Protein–Metal Interaction Mechanisms for Antiviral Applications
The atomic‐level understanding of the metal–protein interactions is still unclear to further improve the performance of noble metals in protein modifications. This work supplies critical theoretical insights from the atomic level to demonstrate the interaction behaviors between selective SARS‐CoV‐2 Spike protein fragments and Ag/Au.
Qiuyang Lu +10 more
wiley +1 more source
Zoological transmission of encephalomyocarditis virus in the United States: Virus evolution, host ecology, and capsid antigenicity derived from an outbreak. [PDF]
Adhikari A +9 more
europepmc +1 more source
EPIclip: A Novel Approach for the Production of Decorated Virus-Like Particles Mediated by High-Affinity Protein Binding Partners. [PDF]
Moleda A +8 more
europepmc +1 more source
Molecular Pharming: Advances, Applications, and Future Prospects in Biotechnology and Medicine
ABSTRACT Genetically engineered plants incorporate the use of a novel bioreactor known as molecular pharming, which has a transformative view on the pharmaceutical industry. The technique enables mass production, at a low cost, and reproducibly of a large number of different protein‐based drugs, vaccines, and industrial enzymes. This review‐based study
Md. Hridoy Ahmed +13 more
wiley +1 more source

