Results 1 to 10 of about 231,805 (310)

An Aurora Kinase B–Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes

open access: yesFrontiers in Cell and Developmental Biology, 2020
To identify and analyze the live proliferating cardiomyocytes is crucial for deciphering the mechanisms controlling endogenous cardiac regeneration. Traditional methods confuse cell division with multinucleation in postnatal cardiomyocytes.
Wenbin Fu   +22 more
doaj   +1 more source

Pulmonary Hypertension-Associated Right Ventricular Cardiomyocyte Remodelling Reduces Treprostinil Function

open access: yesCells, 2023
(1) Pulmonary hypertension (PH)-associated right ventricular (RV) failure is linked to a reduction in pulmonary vasodilators. Treprostinil has shown effectiveness in PAH patients with cardiac decompensation, hinting at potential cardiac benefits.
Aleksandra Judina   +8 more
doaj   +1 more source

AUTOHEMOCHEMOTHERAPY IN CANCER OF THE MAMMARY GLANDS IN CATS

open access: yesВетеринарная патология, 2020
This article discusses one of the options for reducing the post-therapeutic complications caused by antineoplastic drugs used in the treatment of mammary glands cancer in cats. There are various ways to reduce the toxicity of chemotherapy drugs.
V. V. Sukhomlinov
doaj   +1 more source

Myocardial Repair Achieved by the Intramyocardial Implantation of Adult Cardiomyocytes in Combination with Bone Marrow Cells

open access: yesCell Transplantation, 2008
Various cytokines produced by bone marrow cells can protect adult cardiomyocytes against apoptosis. Thus, we investigated the feasibility of implanting adult cardiomyocytes in combination with bone marrow cells for myocardial repair.
Tao-Sheng Li M.D., Ph.D.   +6 more
doaj   +1 more source

Sulfur Dioxide Derivative Prevents the Prolongation of Action Potential During the Isoproterenol-Induced Hypertrophy of Rat Cardiomyocytes

open access: yesAnais da Academia Brasileira de Ciências, 2021
Exogenous SO2 is toxic especially to the pulmonary and cardiovascular system, similar to nitric-oxide, carbon-monoxide, and hydrogen-sulfide. Endogenous SO2 is produced in many cell types.
UĞUR DALAMAN   +4 more
doaj   +1 more source

Unique patterns of cardiogenic and fibrotic gene expression in rat cardiac fibroblasts [PDF]

open access: yesVeterinary World, 2020
Background and Aim: Cardiac fibroblasts are important for both normal and pathological states of the heart, but the knowledge in cell physiology and genomics is still poorly understood.
Kittipong Tachampa, Tuempong Wongtawan
doaj   +1 more source

Role of Mitophagy in Coronary Heart Disease: Targeting the Mitochondrial Dysfunction and Inflammatory Regulation

open access: yesFrontiers in Cardiovascular Medicine, 2022
Coronary heart disease (CHD) is one of the main causes of death worldwide. In the past few decades, several in-depth research on the pathological mechanisms and effective treatment methods for CHD have been conducted.
Mingxuan Liu, Ying Wu
doaj   +1 more source

Impact of Opuntia ficus-indica Fruit Extracts on Toxicity Induced by Doxorubicin in Cardiomyocytes [PDF]

open access: yesResearch Journal of Pharmacognosy
Background and objectives: Doxorubicin is an antineoplastic agent whose administration may cause cardiotoxicity. Opuntia ficus-indica is a widely consumed cactus species with nutritional and antioxidant value.
Leila Safaeian*   +3 more
doaj   +1 more source

The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

open access: yesFrontiers in Pharmacology, 2020
G protein coupled receptor (GPCR) kinases (GRKs) are key regulators of GPCR signaling. Canonical mechanism of GPCR desensitization involves receptor phosphorylation by GRKs followed by arrestin recruitment and uncoupling from heterotrimeric G protein ...
Emiliana Echeverría   +18 more
doaj   +1 more source

The β2-Subunit of Voltage-Gated Calcium Channels Regulates Cardiomyocyte Hypertrophy

open access: yesFrontiers in Cardiovascular Medicine, 2021
L-type voltage-gated calcium channels (LTCCs) regulate crucial physiological processes in the heart. They are composed of the Cavα1 pore-forming subunit and the accessory subunits Cavβ, Cavα2δ, and Cavγ. Cavβ is a cytosolic protein that regulates channel
Simone Pickel   +17 more
doaj   +1 more source

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