Results 31 to 40 of about 127,833 (167)

Zebrafish as a Model System for Brugada Syndrome

Reviews in Cardiovascular Medicine
Brugada syndrome (BrS) is an inheritable cardiac arrhythmogenic disease, associated with an increased risk of sudden cardiac death. It is most common in males around the age of 40 and the prevalence is higher in Asia than in Europe and the United States.
Leonie Verkerk, Arie O. Verkerk, Ronald Wilders   +2 more
doaj   +1 more source

An Integrated Optogenetic and Bioelectronic Platform for Regulating Cardiomyocyte Function

Advanced Science
Bioelectronic medicine is emerging as a powerful approach for restoring lost endogenous functions and addressing life‐altering maladies such as cardiac disorders.
Olurotimi A. Bolonduro, Zijing Chen, Corey P. Fucetola, Yan‐Ru Lai, Megan Cote, Rofiat O. Kajola, Akshita A. Rao, Haitao Liu, Emmanuel S. Tzanakakis, Brian P. Timko   +9 more
doaj   +1 more source

Mitochondria associated membranes in dilated cardiomyopathy: connecting pathogenesis and cellular dysfunction

Frontiers in Cardiovascular Medicine
Dilated cardiomyopathy (DCM) is a leading cause of heart failure, yet therapeutic options remain limited. While traditional research has focused on mechanisms such as energy deficits and calcium dysregulation, increasing evidence suggests that ...
Pingge He, Hongbo Chang, Yueqing Qiu, Zhentao Wang, Zhentao Wang   +4 more
doaj   +1 more source

Combination of Morroniside and Diosgenin Prevents High Glucose-Induced Cardiomyocytes Apoptosis

Molecules, 2017
Cornus officinalis and Dioscorea opposita are two traditional Chinese medicines widely used in China for treating diabetes mellitus and its complications, such as diabetic cardiomyopathy.
Wen-Xia Pi, Xiao-Peng Feng, Li-Hong Ye, Bao-Chang Cai   +3 more
doaj   +1 more source

Hypoxia and TNF‐alpha modulate extracellular vesicle release from human induced pluripotent stem cell‐derived cardiomyocytes

Journal of Extracellular Vesicles
Extracellular vesicles (EVs) have emerged as important mediators of intercellular communication in the heart under homeostatic and pathological conditions, such as myocardial infarction (MI). However, the basic mechanisms driving cardiomyocyte‐derived EV
Margarida Viola, Maarten P. Bebelman, Renee G. C. Maas, Willemijn S. deVoogt, Frederik J. Verweij, Cor S. Seinen, Saskia C. A. deJager, Pieter Vader, Dirk Michiel Pegtel, Joost Petrus Gerardus Sluijter   +9 more
doaj   +1 more source

An immunostaining-based approach for assessing myocardial viability in the infarcted mouse hearts

Frontiers in Cardiovascular Medicine
IntroductionWith the growing need for reliable and precise detection of cell viability in spatial biology, we introduce an antibody-based staining of cardiac troponin I (cTnI) as a simple yet valuable tool for delineating cardiomyocyte viability in the ...
Weili Ouyang, Xueqing Liu, Zheheng Ding, Yanan Ji, Jianfeng Zhao, Hongtao Zhu, Weidong Wu, Zhaoping Ding   +7 more
doaj   +1 more source

Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules

Frontiers in Physiology, 2019
T-tubules are invaginations of the lateral membrane of striated muscle cells that provide a large surface for ion channels and signaling proteins, thereby supporting excitation–contraction coupling. T-tubules are often remodeled in heart failure.
Sarah Helena Vermij, Hugues Abriel, Jan Pavel Kucera   +2 more
doaj   +1 more source

Maturing iPSC-Derived Cardiomyocytes [PDF]

Cells, 2020
Cardiovascular disease is a major cause of mortality worldwide [...]
openaire   +3 more sources

Cardiomyocyte Renewal in Humans [PDF]

Circulation Research, 2012
Pas de ...
Bergmann, Olaf, Zdunek, Sofia, Frisén, Jonas, Bernard, Samuel, Druid, Henrik, Jovinge, Stefan   +5 more
openaire   +4 more sources

Large extracellular vesicles derived from LPS-preconditioned cardiomyocytes alleviate myocarditis via mediating macrophage polarization and modulating p38 MAPK pathway

Frontiers in Immunology
IntroductionMyocarditis is an inflammatory injury to the myocardium characterized by disrupted intercellular communication, involving macrophages and cardiomyocytes as key players.
Yanjie Jiang, Yanjie Jiang, Yanjie Jiang, Yingnan You, Yaxue Xie, Yaxue Xie, Shan Zhou, Mengjie Ma, Bo Han, Bo Han   +9 more
doaj   +1 more source