Results 51 to 60 of about 127,833 (167)

Toward Cardiac Regeneration: Combination of Pluripotent Stem Cell-Based Therapies and Bioengineering Strategies

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Cardiovascular diseases represent the major cause of morbidity and mortality worldwide. Multiple studies have been conducted so far in order to develop treatments able to prevent the progression of these pathologies.
Marta Mazzola   +2 more
doaj   +1 more source

Nanocomposites in 3D Bioprinting for Engineering Conductive and Stimuli‐Responsive Constructs Mimicking Electrically Sensitive Tissue

open access: yesAdvanced NanoBiomed Research, 2022
Rebuilding damaged or diseased tissue by means of biological additive manufacturing has recently gained lot of attention and shown very promising result. Using biofabrication techniques to mimic and replicate natural tissue as well as cell environment is
Fabian Züger   +3 more
doaj   +1 more source

Atrial cardiomyocyte calcium signalling

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011
Whereas Ca(2+) signalling in ventricular cardiomyocytes is well described, much less is known regarding the Ca(2+) signals within atrial cells. This is surprising given that atrial cardiomyocytes make an important contribution to the refilling of ventricles with blood, which enhances the subsequent ejection of blood from the heart.
Bootman, Martin D.   +4 more
openaire   +3 more sources

Cardiac Muscle Cell‐Based Coupled Oscillator Network for Collective Computing

open access: yesAdvanced Intelligent Systems, 2021
Current rate of data generation and the need for real‐time data analytics can benefit from new computational approaches where computation proceeds in a massively parallel way while being scalable and energy efficient.
Xiang Ren   +8 more
doaj   +1 more source

Fractalkine Depresses Cardiomyocyte Contractility

open access: yesPLoS ONE, 2013
Our laboratory reported that male mice with cardiomyocyte-selective knockout of the prostaglandin E2 EP4 receptor sub-type (EP4 KO) exhibit reduced cardiac function. Gene array on left ventricles (LV) showed increased fractalkine, a chemokine implicated in heart failure. We therefore hypothesized that fractalkine is regulated by PGE2 and contributes to
David Taube   +5 more
openaire   +4 more sources

Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes

open access: yesFrontiers in Cell and Developmental Biology
IntroductionDoxorubicin (DOX) is a highly effective anti-cancer drug, but its clinical applications are limited by its cardiotoxicity. The mechanisms underlying DOX-induced cardiotoxicity (DIC) remain incompletely understood.
Minxia Ke   +7 more
doaj   +1 more source

MicroRNAs in cardiomyocyte development [PDF]

open access: yesWIREs Systems Biology and Medicine, 2010
AbstractMicroRNAs (miRNAs) negatively regulate gene expression at the post‐ transcriptional level, primarily by base‐pairing with the 3′‐untranslated region (3′‐UTR) of their target mRNAs. Many miRNAs are expressed in a tissue/organ‐specific manner and are associated with an increasing number of cell proliferation, differentiation, and tissue ...
Andrea P, Malizia, Da-Zhi, Wang
openaire   +2 more sources

Molecular Communications For Cardiomyocytes

open access: yes39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2017
The continued miniaturization of electronics makes it realistic to monitor internal cardiac disease processes by wireless implantable medical sensors and actuators incorporated in implantable cardiac devices. In order to deal with some cardiac diseases, this paper introduces the molecular communication methods for cardiac muscle cell communications.
Lu, Pengfei   +3 more
openaire   +1 more source

Understanding Greater Cardiomyocyte Functions on Aligned Compared to Random Carbon Nanofibers in PLGA [Corrigendum]

open access: yesInternational Journal of Nanomedicine, 2021
Asiri A, Marwani H, Khan SB, Webster T. Int J Nanomedicine. 2015;10(1):89–96.   The authors have advised the note section for Figure 1 on page 90 is incorrect. The correct Notes section is as follows: Notes: SEM images showing the distribution
Asiri A, Marwani H, Khan SB, Webster T
doaj  

Non-genomic Effects of Estrogen on Cell Homeostasis and Remodeling With Special Focus on Cardiac Ischemia/Reperfusion Injury

open access: yesFrontiers in Endocrinology, 2019
This review takes into consideration the main mechanisms involved in cellular remodeling following an ischemic injury, with special focus on the possible role played by non-genomic estrogen effects. Sex differences have also been considered.
Rossella Puglisi   +6 more
doaj   +1 more source

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