Results 61 to 70 of about 231,805 (310)

An immunostaining-based approach for assessing myocardial viability in the infarcted mouse hearts

Frontiers in Cardiovascular Medicine
IntroductionWith the growing need for reliable and precise detection of cell viability in spatial biology, we introduce an antibody-based staining of cardiac troponin I (cTnI) as a simple yet valuable tool for delineating cardiomyocyte viability in the ...
Weili Ouyang, Xueqing Liu, Zheheng Ding, Yanan Ji, Jianfeng Zhao, Hongtao Zhu, Weidong Wu, Zhaoping Ding   +7 more
doaj   +1 more source

Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules

Frontiers in Physiology, 2019
T-tubules are invaginations of the lateral membrane of striated muscle cells that provide a large surface for ion channels and signaling proteins, thereby supporting excitation–contraction coupling. T-tubules are often remodeled in heart failure.
Sarah Helena Vermij, Hugues Abriel, Jan Pavel Kucera   +2 more
doaj   +1 more source

Sex‐specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles [PDF]

, 2018
Sex has a large influence on cardiac electrophysiological properties. Whether sex differences exist in apamin‐sensitive small conductance Ca2+‐activated K+ (SK) current (IKAS) remains unknown.
Chen, Mu, Chen, Peng-Sheng, Chen, Zhenhui, Everett, Thomas H., IV, Guo, Shuai, Lin, Shien-Fong, Rubart-von der Lohe, Michael, Wang, Zhuo, Weiss, James N., Xu, Dong-Zhu, Yin, Dechun   +10 more
core   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Large extracellular vesicles derived from LPS-preconditioned cardiomyocytes alleviate myocarditis via mediating macrophage polarization and modulating p38 MAPK pathway

Frontiers in Immunology
IntroductionMyocarditis is an inflammatory injury to the myocardium characterized by disrupted intercellular communication, involving macrophages and cardiomyocytes as key players.
Yanjie Jiang, Yanjie Jiang, Yanjie Jiang, Yingnan You, Yaxue Xie, Yaxue Xie, Shan Zhou, Mengjie Ma, Bo Han, Bo Han   +9 more
doaj   +1 more source

Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes

Frontiers in Cell and Developmental Biology, 2017
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CM) represent a potential unlimited cell supply for cardiac tissue engineering and possibly regenerative medicine applications.
Xuetao Sun, Sara S. Nunes, Sara S. Nunes, Sara S. Nunes   +3 more
doaj   +1 more source

Cre-loxP-mediated genetic lineage tracing: Unraveling cell fate and origin in the developing heart

Frontiers in Cardiovascular Medicine, 2023
The Cre-loxP-mediated genetic lineage tracing system is essential for constructing the fate mapping of single-cell progeny or cell populations. Understanding the structural hierarchy of cardiac progenitor cells facilitates unraveling cell fate and origin
Tao Wang, Xinzhe Chen, Kai Wang, Jie Ju, Xue Yu, Shaocong Wang, Cuiyun Liu, Kun Wang   +7 more
doaj   +1 more source

Modeling the Heart as a Communication System [PDF]

, 2014
Electrical communication between cardiomyocytes can be perturbed during arrhythmia, but these perturbations are not captured by conventional electrocardiographic metrics.
Aguilar-Rodríguez, José, Ashikaga, Hiroshi, Garland, Joshua, Gorsky, Shai, Lusczek, Elizabeth, Marquitti, Flávia Maria Darcie, Thompson, Brian, Wu, Degang   +7 more
core   +2 more sources

Maturing iPSC-Derived Cardiomyocytes [PDF]

Cells, 2020
Cardiovascular disease is a major cause of mortality worldwide [...]
openaire   +3 more sources

Cardiomyocyte Renewal in Humans [PDF]

Circulation Research, 2012
Pas de ...
Bergmann, Olaf, Zdunek, Sofia, Frisén, Jonas, Bernard, Samuel, Druid, Henrik, Jovinge, Stefan   +5 more
openaire   +4 more sources