Role of X-linked Inhibitor of Apoptosis Protein as Cancer Biomarker [PDF]
Journal of Clinical and Diagnostic Research, 2017 X-linked Inhibitor of Apoptosis Protein (XIAP), is one of the most important apoptotic inhibitors that plays a vital role in regulating various aspects of cell functions including cell cycle progression, arrest, and apoptosis.
Manoj Pandey +3 more
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Investigation of the cellular response to bone fractures: evidence for flexoelectricity [PDF]
Scientific Reports volume 10, Article number: 254 (2020), 2020 The recent discovery of bone flexoelectricity (electrical polarization induced by strain gradient) suggests that flexoelectricity could have physiological effects in bones, and specifically near bone fractures, where flexoelectricity is theoretically highest. Here, we report a cytological study of the interaction between crack stress and bone cells. We
arxiv +1 more source
Clinical and Translational Medicine, 2022 Background Anaplastic thyroid carcinoma (ATC) is one of the most aggressive tumours. We previously confirmed that apatinib has potential therapeutic effects on ATC via regulated cell death (RCD).
Qiwu Zhao +12 more
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Anticancer Effect of Fluorouracil and Gum-Based Cerium Oxide Nanoparticles on Human Malignant Colon Carcinoma Cell Line (Caco2) [PDF]
Cell Journal, 2023 Objective: We investigated whether co-incubation of 5-FU and gum-based cerium oxide nanoparticles (CeO2 NPs) would improve half-maximal inhibitory concentration (IC50) and apoptosis in the Caco-2 cancer cell lineMaterials and Methods: In this ...
Zahra Keramati +3 more
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Structure and Activation Mechanism of the Drosophila Initiator Caspase Dronc [PDF]
, 2006 Activation of an initiator caspase is essential to the execution of apoptosis. The molecular mechanisms by which initiator caspases are activated remain poorly understood.
Demeler, Borries +5 more
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ILP-2: A New Bane and Therapeutic Target for Human Cancers
Frontiers in Oncology, 2022 Inhibitor of apoptosis protein-related-like protein-2 (ILP-2), also known as BIRC-8, is a member of the inhibitor of apoptosis protein (IAPs) family, which mainly encodes the negative regulator of apoptosis.
Zhiliang Zhang +11 more
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Features of a necrotic and inflammatory process in different forms of nonalcoholic fatty liver disease [PDF]
Терапевтический архив, 2017 Aim. To identify the features of development of a necrotic and inflammatory process in different forms of nonalcoholic fatty liver disease (NAFLD), by comparatively analyzing a full set of clinical and laboratory parameters, including the cytokine status
I V Kurbatova, O P Dudanova
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Cell Death Triggers Induce MLKL Cleavage in Multiple Myeloma Cells, Which may Promote Cell Death
Frontiers in Oncology, 2022 Necroptosis is a type of caspase-independent programmed cell death that has been implicated in cancer development. Activation of the canonical necroptotic pathway is often characterized with successive signaling events as the phosphorylation of mixed ...
Jing Chen +6 more
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Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia. [PDF]
, 2014 Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International Licence.
A Castano +30 more
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Caspases: An apoptosis mediator
Journal of Advanced Veterinary and Animal Research, 2015 The process of programmed cell death, or apoptosis, is generally characterized by distinct morphological characteristics and energy - dependent biochemical mechanisms.
Tapan Kumar Palai, Smruti Ranjan Mishra
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