Results 11 to 20 of about 9,499 (202)
Cathelicidins: Immunomodulatory Antimicrobials [PDF]
Vaccines, 2018 Cathelicidins are host defense peptides with antimicrobial and immunomodulatory functions. These effector molecules of the innate immune system of many vertebrates are diverse in their amino acid sequence but share physicochemical characteristics like ...
Roel M. van Harten +3 more
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Cathelicidins Modulate TLR-Activation and Inflammation [PDF]
Frontiers in Immunology, 2020 Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are more and more appreciated for their immunomodulatory ...
Maaike R. Scheenstra +5 more
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Snake Venom Cathelicidins as Natural Antimicrobial Peptides [PDF]
Frontiers in Pharmacology, 2019 Bioactive small molecules isolated from animals, plants, fungi and bacteria, including natural antimicrobial peptides, have shown great therapeutic potential worldwide.
Elizângela de Barros +14 more
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Cathelicidins In Humans And Animals [PDF]
Postępy Mikrobiologii, 2019 Cathelicidins are Important immunological peptides – HDPs (Host Defense Peptides) with high biological activity in mammals, including human and vertebrate animals.
Deptuła Jakub +4 more
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Antiviral Potential of Cathelicidins [PDF]
Future Microbiology, 2013 The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow. As our understanding of innate immunity has expanded over recent years, knowledge of natural host defenses against viral infections has started to offer potential for novel therapeutic strategies.
Barlow, Peter G. +3 more
openaire +4 more sources
Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium
Journal of Innate Immunity, 2022 Cathelicidin peptides secreted by leukocytes and epithelial cells are microbicidal but also regulate pathogen sensing via toll-like receptors (TLRs) in the colon by mechanisms that are not fully understood.
Ravi Holani +9 more
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Entamoeba histolytica Induces Intestinal Cathelicidins but Is Resistant to Cathelicidin-Mediated Killing [PDF]
Infection and Immunity, 2012 ABSTRACTThe enteric protozoan parasiteEntamoeba histolyticais the cause of potentially fatal amebic colitis and liver abscesses.E. histolyticatrophozoites colonize the colon, where they induce inflammation, penetrate the mucosa, and disrupt the host immune system. The early establishment ofE.
Eduardo R, Cobo +7 more
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Scientific Reports, 2023 The Tasmanian devil (Sarcophilus harrisii) is endangered due to the spread of Devil Facial Tumour Disease (DFTD), a contagious cancer with no current treatment options.
Cleopatra Petrohilos +4 more
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Dodecapeptide Cathelicidins of Cetartiodactyla: Structure, Mechanism of Antimicrobial Action, and Synergistic Interaction With Other Cathelicidins [PDF]
Frontiers in Microbiology, 2021 In this study, dodecapeptide cathelicidins were shown to be widespread antimicrobial peptides among the Cetruminantia clade. In particular, we investigated the dodecapeptide from the domestic goat Capra hircus, designated as ChDode and its unique ortholog from the sperm whale Physeter catodon (PcDode).
Ilia A. Bolosov +12 more
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Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics. [PDF]
PLoS ONE, 2008 BACKGROUND: Cathelicidins are a family of antimicrobial peptides acting as multifunctional effector molecules of innate immunity, which are firstly found in mammalians. Recently, several cathelicidins have also been found from chickens and fishes.
Yipeng Wang +8 more
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