Results 31 to 40 of about 9,499 (202)

Significance and Diagnostic Role of Antimicrobial Cathelicidins (LL-37) Peptides in Oral Health

Biomolecules, 2017
Cathelicidins are a group of oral antimicrobial peptides that play multiple vital roles in the human body, such as their antimicrobial (broad spectrum) role against oral microbes, wound healing, and angiogenesis, with recent evidences about their role in
Zohaib Khurshid, Mustafa Naseem, Faris Yahya I. Asiri, Maria Mali, Rabia Sannam Khan, Haafsa Arshad Sahibzada, Muhammad Sohail Zafar, Syed Faraz Moin, Erum Khan   +8 more
doaj   +1 more source

Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics [PDF]

, 2016
Mastitis, inflammation of the mammary gland, is the most common and costly disease of dairy cattle in the western world. It is primarily caused by bacteria, with Streptococcus uberis as one of the most prevalent causative agents.
Burchmore, Richard, Eckersall, Peter, Herzyk, Pawel, McLaughlin, Mark, Mcneilly, Tom, Mudaliar, Manikhandan, Tassi, Riccardo, Thomas, Funmilola, Weidt, Stefan, Wilson, David, Zadoks, Ruth   +10 more
core   +1 more source

Vitamin D and immunity [PDF]

, 2014
Vitamin D deficiency has been linked to an increased risk of a wide range of adverse health outcomes. The active form of vitamin D has an important role in calcium metabolism and in bone mineralisation, but the evidence for other health outcomes is mixed,
Geldenhuys, Sian, Gorman, Shelley, Hart, Prue, Lucas, Robyn   +3 more
core   +1 more source

Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]

, 2012
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Albiol Matanic VC, Bayerl C, Berg M, Blount BW, Boguniewicz M, Bourinbaiar AS, Bradshaw J, Brogden NK, Brown JM, Carretero M, Christophers E, Ciornei CD, Conner K, Cork MJ, de Jongh GJ, Degitz K, Dempsey CE, Dubos RJ, Eiseman AS, Epand RF, Erdag G, Escher N, Falagas ME, Ge Y, Giacometti A, Glaser R, Gläser R, Gregory SM, Grossgebauer K, Guarna M, Guiliani A, Guttman-Yassky E, Hancock RE, Harder J, Harder J, Harder J, Hartmann D, Howell MD, Huttner KM, Imura Y, Jacob L, Jacobsen F, Jung K, Khandelia H, Koch-Weser J, Koczulla R, Korting HC, Kotlan B, Kretschmar M, Kretschmar M, Kretschmar M, Kreuter A, Kruse T, Lai Y, Lai YP, Lande R, Li Q, Lind HE, Liu AY, Madsen P, Mallow EB, Marincola FM, Maroti G, Melo MN, Mogi T, Muramatsu I, Nagy I, Nijnik A, Nomura I, Nussenblatt RB, Ong PY, Oono T, Pivarcsi A, Plebani M, Reddy KVR, Reddy KVR, Rieg S, Risso A, Ruckdeschel G, Rudolph B, Sader HS, Schauber J, Schauber J, Schittek B, Schittek B, Schneider JJ, Schröder JM, Schön MP, Seoh SA, Shai Y, Sigurdadottir T, Simmaco M, Steinstraesser L, Steinstraesser L, Steinstraesser L, Storm DR, Svinarich DM, Tang YQ, Voigt HU, Wang G, Wang Z, Willenberg W, Yamasaki K, Yamasaki K, Zairi A, Zanger P, Zasloff M   +106 more
core   +1 more source

Genetic diversity of Japanese quail cathelicidins

Poultry Science, 2021
Japanese quail is a low-fat, meat-bird species exhibiting high disease resistance. Cathelicidins (CATHs) are host defense peptides conserved across numerous vertebrate species that play an important role in innate immunity. The activity of host defense peptides can be affected by amino acid substitutions.
Taichiro Ishige, Hiromi Hara, Takashi Hirano, Tomohiro Kono, Kei Hanzawa   +4 more
openaire   +3 more sources

Cathelicidin Antimicrobial Peptides with Reduced Activation of Toll-Like Receptor Signaling Have Potent Bactericidal Activity against Colistin-Resistant Bacteria

mBio, 2016
The world is at the precipice of a postantibiotic era in which medical procedures and minor injuries can result in bacterial infections that are no longer effectively treated by antibiotics.
Cheng Kao, Xiaoyan Lin, Guanghui Yi, Yunliang Zhang, Dean A. Rowe-Magnus, Karen Bush   +5 more
doaj   +1 more source

Structural and functional analysis of the pro-domain of human cathelicidin, LL-37 [PDF]

, 2013
Cathelicidins form a family of small host defense peptides distinct from another class of cationic antimicrobial peptides, the defensins. They are expressed as large precursor molecules with a highly conserved pro-domain known as the cathelin-like domain
Beckley, Amy J., Ericksen, Bryan, Lan, Liqiong, Li, Xiangdong, Ling, Minhua, Lu, Wuyuan, Pazgier, Marzena, Pozharski, Edwin, Shi, Jishu N., Toth, Eric, Yuan, Weirong, Zhan, Changyou, Zou, Guozhang   +12 more
core   +1 more source

Molecular Cloning, Expression Analyses, and Physiological Roles of Cathelicidins in the Bursa of Fabricius of the Japanese Quail, Coturnix japonica

Antibiotics, 2023
Antimicrobial peptides (AMPs) act directly on pathogens and maintain the anti-inflammatory effects and activation of immunocompetent cells. Therefore, the activation of the immune system in poultry via the elevation of endogenous AMPs has been attempted.
Takumi Ikeda, Hirotada Kondo, Daiki Nunomura, Genki Sato, Machi Ito, Nanako Yamanaka, Shawichi Iwamuro, Itaru Hasunuma, Sakae Kikuyama, Tetsuya Kobayashi   +9 more
doaj   +1 more source

Streptococcal M1 Strikes by Neutralizing Cathelicidins [PDF]

Cell Host & Microbe, 2015
Virulent group A streptococci have become a serious threat, with the emergence of the hypervirulent lineage M1T1. In this issue of Cell Host & Microbe, LaRock et al. (2015), uncover a role for the streptococcal M1 protein in neutralizing a key human antimicrobial peptide, cathelicidin.
Henriques-Normark, Birgitta, Normark, Staffan   +1 more
openaire   +2 more sources

Molecular Mechanisms Used by Salmonella to Evade the Immune System [PDF]

, 2017
Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated immune defenses of their hosts. Several serovars of the Gram-negative bacterium Salmonella enterica have been used as models for the study of pathogen-host ...
Bernal Bayard, Joaquín, Ramos Morales, Francisco   +1 more
core   +1 more source