Results 81 to 90 of about 9,499 (202)

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Regulation of Gut Antimicrobial Peptides and Cytokines Expression in Broiler Chicks Challenged by Campylobacter jejuni Lipopolysaccharides [PDF]

Brazilian Journal of Poultry Science
This study evaluated the effect of probiotics on antimicrobial peptides and cytokines’ mRNA synthesis in the proventriculus and cecum of broiler chicks exposed to Campylobacter jejuni lipopolysaccharides (LPS).
ESI Mohammed, M Al-Rasheed, MS Ahmed
doaj   +1 more source

Effect of antimicrobial peptides on planktonic growth, biofilm formation and biofilm-derived bacterial viability of Streptococcus pneumoniae

Southern African Journal of Infectious Diseases, 2021
Streptococcus pneumoniae is a leading cause of pneumonia mortality globally. Pneumococcal disease is often associated with prolonged colonisation of hosts and this process is facilitated by biofilm formation that is largely resistant to conventional ...
Michael T. Boswell, Riana Cockeran
doaj   +1 more source

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review

International Journal of Dermatology, EarlyView.
(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Marie‐Eline Pauline Henriette Debeuf, Maartje Hendrika Pieternel Rauwenhoff, Michel van Geel, Peter Martin Steijlen, Valerie Lydie Roland Marc Verstraeten   +4 more
wiley   +1 more source

LL37, a human antimicrobial peptide with immunomodulatory properties [PDF]

, 2011
Cationic antimicrobial peptides (AMPs) represent the first line of defense against many invading pathogens. These small amphipathic peptides are part of the innate immune system and have a broad-spectrum activity against bacteria, fungi and viruses. In
Domingues, Lucília, Gama, F. M., Ramos, Reinaldo Rodrigues   +2 more
core  

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

New trends in peptide-based anti-biofilm strategies : a review of recent achievements and bioinformatics approaches [PDF]

, 2012
Antimicrobial peptides (AMPs) have a broad spectrum of activity and unspecific mechanisms of action. Therefore, they are seen as valid alternatives to overcome clinically relevant biofilms and reduce the chance of acquired resistance.
Anália Lourenço, Fernandes FC, Glinel K, Hamilton M, Iwasaki T, Jorge P, Jorgensen JH, Kim SS, Magrane M, Maria Olívia Pereira, Nakamura T, Oppenheim FG, Paula Jorge, Pestana-Calsa MC, Rapaport D, Rex JH, Rex JH, Rosa R, Sai KP, Schober D, Wikipedia, Wikler MA, Wikler MA, Zairi A, Zamyatnin AA, Zhang T   +25 more
core   +1 more source

Prognostic Significance of the Pretreatment Neutrophil‐to‐Lymphocyte Ratio and Tumor‐Associated Neutrophils in Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives The prognostic significance of the neutrophil‐to‐lymphocyte ratio (NLR) and tumor‐associated neutrophils (TANs) in head and neck squamous cell carcinoma (HNSCC) remains a subject of considerable research interest. This systematic review and meta‐analysis aimed to evaluate the relationship between pretreatment NLR and TANs and ...
Ahana Kapuge Dona Varuni Yashodha Ratnayake, Aini Hyytiäinen, Georgia Vasiliki Gkountana, Meri Torri, Ahmed Al‐Samadi   +4 more
wiley   +1 more source

Neutrophils and macrophages: the main partners of phagocyte cell systems [PDF]

, 2012
Biological cellular systems are groups of cells sharing a set of characteristics, mainly key function and origin. Phagocytes are crucial in the host defense against microbial infection.
Neves, Margarida Correia, Silva, Manuel T.   +1 more
core   +1 more source