Results 21 to 30 of about 47,172 (255)

Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance Development

Frontiers in Physiology, 2020
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders.
Maider Varela-Guruceaga, Elise Belaidi, Lucie Lebeau, Ella Aka, Ramaroson Andriantsitohaina, Sophie Giorgetti-Peraldi, Claire Arnaud, Soazig Le Lay   +7 more
doaj   +1 more source

Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL. [PDF]

, 2019
Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this
Dobrow, Sebastian, Flores, Claudia, Linden, Jennifer R, Michel, Adam O, Schmidt, Eric F, Uzal, Francisco A, Valenzuela, Marissa, Vartanian, Timothy   +7 more
core   +1 more source

Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP

Cell Reports, 2018
Summary: The transcriptional regulator YAP orchestrates many cellular functions, including tissue homeostasis, organ growth control, and tumorigenesis.
Roberto Moreno-Vicente, Dácil María Pavón, Inés Martín-Padura, Mauro Català-Montoro, Alberto Díez-Sánchez, Antonio Quílez-Álvarez, Juan Antonio López, Miguel Sánchez-Álvarez, Jesús Vázquez, Raffaele Strippoli, Miguel A. del Pozo   +10 more
doaj   +1 more source

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. [PDF]

, 2001
Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor-mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and the other to the ...
Chiang, SH, Kanzaki, M, Macara, IG, Mora, S, Pessin, JE, Saltiel, AR, Shigematsu, S, Watson, RT   +7 more
core   +3 more sources

Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections

Viruses, 2020
Virus infection has drawn extensive attention since it causes serious or even deadly diseases, consequently inducing a series of social and public health problems.
Yifan Xing, Zeyu Wen, Wei Gao, Zhekai Lin, Jin Zhong, Yaming Jiu   +5 more
doaj   +1 more source

Selective Cholesterol Dynamics between Lipoproteins and Caveolae/Lipid Rafts [PDF]

, 2007
Although low-density lipoprotein (LDL) receptor-mediated cholesterol uptake through clathrin-coated pits is now well understood, the molecular details and organizing principles for selective cholesterol uptake/efflux (reverse cholesterol transport, RCT ...
Atshaves, Barbara P., Ball, Judith M., Gallegos, Adalberto M., Kier, Ann B., Landrock, Kerstin K., Martin, Gregory G., McIntosh, Avery L., Parr, Rebecca D., Schroeder, Friedhelm, Storey, Stephen M.   +9 more
core   +2 more sources

Caveolae in Rabbit Ventricular Myocytes: Distribution and Dynamic Diminution after Cell Isolation [PDF]

, 2017
Caveolae are signal transduction centers, yet their subcellular distribution and preservation in cardiac myocytes after cell isolation are not well documented.
Alexander D. Corbett, Andreas Hoenger, Aravamudan, Baczkó, Balijepalli, Balijepalli, Bozzola, Brette, Bub, Bősze, Calaghan, Calaghan, Carozzi, Cheng, Di Maio, Drab, Dulhunty, Eva A. Rog-Zielinska, Forbes, Galbiati, Galiñanes, Gil Bub, Golowasch, Groulx, Hagiwara, Hansen, Harken, Harvey, Hayashi, Head, Hong, Ilona Bodi, Iribe, Ishikawa, Jayasinghe, Judith Sheldon, Jung, Karnovsky, Kawamura, Kohl, Kong, Kozera, Kremer, Levin, Liu, Louch, Löhn, Macdougall, Maguy, Martin Fink, Mastronarde, Mitcheson, Mitcheson, Mundy, Murata, Nerbonne, Ostrom, Palade, Panfilov, Parton, Parton, Pavlović, Pelkmans, Pelkmans, Pelkmans, Peter Kohl, Peyronnet, Pfeiffer, Quinn, Razani, Rebecca A.B. Burton, Rog-Zielinska, Rothberg, Rybin, Rémi Peyronnet, Sarah C. Calaghan, Savio-Galimberti, Scardigli, Scherer, Scriven, Sens, Serna, Simons, Sinha, Song, Stahlhut, Stan, Steinberg, Sun, Tang, Trump, Valentin, Wagner, Way, Wong, Woodman, Wright, Yaniv   +97 more
core   +2 more sources

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +8 more sources

EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription [PDF]

, 2018
Caveolae are small invaginated pits that function as dynamic mechanosensors to buffer tension variations at the plasma membrane. Here we show that under mechanical stress, the EHD2 ATPase is rapidly released from caveolae, SUMOylated, and translocated to
Alexandre Grassart, Ariotti, Bolte, Catherine Coirault, Cesar Augusto Valades-Cruz, Chan, Chen, Cheng, Christine Viaris de Lesegno, Christophe Lamaze, Cédric M. Blouin, Darius Köster, DuFort, Edelstein, Enserink, Fernández-Sánchez, Gambin, Garcia, Geiss-Friedlander, Gervásio, Goetz, Heuser, Hoernke, Iskratsch, Joshi, Kovtun, Lamaze, Lamaze, Li, Lim, Liu, Lo, Ludger Johannes, Ludwig, Morén, Nassar, Nassoy, Otsu, Palade, Paolo Pierobon, Pekar, Pierre Bost, Satish Kailasam Mani, Sheetz, Shi, Sinha, Stoeber, Stoeber, Stéphane Vassilopoulos, Stéphanie Torrino, Subramanian, Söderberg, Tolić-Nørrelykke, Valérie Chambon, Vassili Soumelis, Wei-Wei Shen, Yamada, Yang, Yeow   +58 more
core   +4 more sources

Caveolae as Potential Hijackable Gates in Cell Communication

Frontiers in Cell and Developmental Biology, 2020
Caveolae are membrane microdomains described in many cell types involved in endocytocis, transcytosis, cell signaling, mechanotransduction, and aging. They are found at the interface with the extracellular environment and are structured by caveolin and ...
Maria Dudãu, Maria Dudãu, Elena Codrici, Cristiana Tanase, Cristiana Tanase, Mihaela Gherghiceanu, Mihaela Gherghiceanu, Ana-Maria Enciu, Ana-Maria Enciu, Mihail E. Hinescu, Mihail E. Hinescu   +10 more
doaj   +1 more source