Results 1 to 10 of about 4,839 (128)

Prognostic value of cross‐lineage expression of the myeloid‐associated antigens CD13 and CD33 in adult B‐lymphoblastic leukemia: A large real‐world study of 1005 patients

Cancer Medicine, 2023
Background Cross‐lineage expression of the myeloid‐associated antigens CD13/CD33 is common in adult B‐lymphoblastic leukemia (B‐ALL) patients, yet its prognostic value is still controversial.
Hongyan Liao, Hongli Lai, Jiao Chen, Xiao Shuai, Xin Zhang, Ying Yang, Mengyuan Lyu, Qin Zheng   +7 more
doaj   +3 more sources

CD13 is a bona-fide marker of bovine pre-adipocytes with potential in cultivated fat applications [PDF]

npj Science of Food
Despite its significant potential, cultivated fat manufacture remains a relatively inefficient process, as it primarily uses source preparations of animal-derived mesenchymal stem/stromal cells (MSC) that are poorly defined and highly heterogenous in ...
Seungmee Lee, Thomas Thrower, Susanna E. Riley, Cristina L. Esteves, F. Xavier Donadeu   +4 more
doaj   +2 more sources

Immunophenotypic abnormality quantification refines multiparameter flow cytometry-based measurable residual disease testing in adults allografted for acute myeloid leukemia in morphologic remission. [PDF]

Hemasphere
Abstract Flow cytometry‐based measurable residual disease (MRD) testing is routinely used in acute myeloid leukemia (AML), but methodologies need refinement to optimize assay characteristics. Here, we examined 1215 adults with AML or myelodysplastic syndrome/AML allografted in morphologic remission to study how the type(s) of leukemic blasts and degree/
Le CM, Chen X, Kodaira S, Othus M, Gang M, Davis C, Basom RS, Cherian S, Walter RB.   +8 more
europepmc   +2 more sources

Acute Myeloid Leukemia Secondary to Radiation Therapy for Rectal Cancer: A Case Report. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Therapy‐related AML (t‐AML) is a subtype of acute myeloid leukemia (AML) that arises in the bone marrow and primarily affects white blood cells. It is associated with prior exposure to cytotoxic agents, including chemotherapy and radiotherapy. The risk of the disease increases with age and treatment intensity.
Alkhaledi A, Hussaen LA, Kahla L, Sammoud B, Ghanem SG.   +4 more
europepmc   +2 more sources

Comprehensive omics-based classification system in adult patients with B-cell acute lymphoblastic leukemia. [PDF]

Mol Oncol
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Song Y, Liu T, Hao Q, Fang Q, Gong X, Li Y, Tian Z, Wei H, Wang M, Wang J, Cheng T, Mi Y.   +11 more
europepmc   +2 more sources

Tissue-Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts. [PDF]

Am J Hematol
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Valent P, Wojta J, Kovanen PT, Hermine O, Fend F, Sotlar K, Greinix H, Geissler K, Hartmann K, Schwaab J, Herling M, Boccuni L, Kazianka L, John MV, Sperr WR, Zierfuss C, Tzankov A, Sillaber C, Minkov M, Hoermann G, Collin M, Horny HP, Haferlach T, Sibilia M, Haroche J, La Rosée P, Orfao A, Arock M.   +27 more
europepmc   +2 more sources

Immunophenotypic Aberrancies in Acute Leukemia: A Tertiary Care Centre Experience

Oman Medical Journal, 2021
Objectives: Acute leukemias (AL) are a heterogeneous group of hematological malignancies with the presence of 20% or more blasts in the peripheral blood or bone marrow.
Monika Gupta, Lovekesh Monga, Dimple Mehrotra, Sonia Chhabra, Shivani Singhal, Rajeev Sen   +5 more
doaj   +1 more source

Characterization of CD13 and CD33 Surface Antigen–Negative Acute Myeloid Leukemia [PDF]

American Journal of Clinical Pathology, 2000
From a cohort of 220 adults with newly diagnosed acute myeloid leukemia (AML), 8 (3.6%) exhibited a rare variant of aberrant membrane phenotype. It was characterized with typical myeloid morphologic and cytochemical patterns and absence of myeloid associated antigens (CD13, CD33, CD14, glycophorin A, CD61).
N, Kraguljac, D, Marisavljevic, G, Jankovic, N, Radosevic, M, Pantic, M, Donfrid, N, Miletic, D, Boskovic, M, Colovic   +8 more
openaire   +2 more sources

Multiple gastric involvement by myeloid antigen CD13‐positive non‐secretory plasma cell leukaemia [PDF]

British Journal of Haematology, 1996
Gastrointestinal tract involvement is a rare complication of plasma cell neoplasia. We present a case of non‐secretory type primary plasma cell leukaemia (PCL) with multiple gastric involvement. Dual surface antigen analysis of bone marrow cells revealed that atypical plasma cells coexpressed CD38 and myeloid antigen CD13.
A, Ohsaka, N, Sato, Y, Imai, S, Hirai, Y, Oka, M, Kikuchi, A, Takahashi   +6 more
openaire   +2 more sources

Spectrum of immunophenotypic aberrancies in acute leukemia along with their correlation with adverse hematological parameters

Indian Journal of Health Sciences and Biomedical Research KLEU, 2022
BACKGROUND: The identification of aberrant phenotypes in acute leukemia is crucial for treatment monitoring and minimal residual disease analysis.
Sana Ahuja, Avneesh Malviya
doaj   +1 more source