Results 31 to 40 of about 88,420 (193)
, 2018 IL-10 is a potent immunosuppressive cytokine that promotes the differentiation of tolerogenic dendritic cells (DC-10), and the subsequent induction of antigen-specific T regulatory type 1 (Tr1) cells, which suppress immune responses.
Maria Grazia Roncarolo (78316) +5 more
core +1 more source
A Potential Inhibitory Profile of Liver CD68+ Cells during HCV Infection as Observed by an Increased CD80 and PD-L1 but Not CD86 Expression. [PDF]
PLoS ONE, 2016 AIM:The lack of potent innate immune responses during HCV infection might lead to a delay in initiating adaptive immune responses. Kupffer cells (KCs) and liver-infiltrating monocytes/macrophages (CD68+ cells) are essential to establish effective anti ...
Elias A Said +9 more
doaj +1 more source
CD80 and CD86 Control Antiviral CD8+ T-Cell Function and Immune Surveillance of Murine Gammaherpesvirus 68 [PDF]
, 2006 The interactions between CD80 and CD86 on antigen-presenting cells and CD28 on T cells serve as an important costimulatory signal in the activation of T cells.
Zhang, Weijun +5 more
core +1 more source
BMC Immunology, 2020 Background The use of anti-B cell based therapies in immune-mediated diseases targeting general B cell markers or molecules important for B cell function has increased the clinical needs of monitoring B cell subpopulations.
Susanne Axelsson +5 more
doaj +1 more source
Soluble CD86 Is a Costimulatory Molecule for Human T Lymphocytes [PDF]
Immunity, 2000 CD86 is an important costimulatory molecule for the priming and activation of naive and memory T cells, respectively. Here, we show that soluble CD86 is detected in human serum. Soluble CD86 is produced by resting monocytes and results from an alternatively spliced transcript (CD86deltaTM) characterized by deletion of the transmembrane domain ...
Jeannin, Pascale +11 more
openaire +3 more sources
Significance of infiltration of M1 tumor-associated macrophages in hepatocellular carcinoma [PDF]
Zhongguo aizheng zazhiBackground and purpose: Tumor-associated macrophages (TAM) as the main stromal cells in the tumor microenvironment play an important role in tumor progression.
Feng XIAO +5 more
doaj +2 more sources
Kinetics of CD83 and CD86 upregulation.
, 2013 Isolated pDCs from HIV negative donors were treated with Influenza (M.O.I = 0.5), imiquimod (20 µg/ml), or HIV (M.O.I = 0.5) for various time points and harvested for analysis by flow cytometry for surface expression of CD83 and CD86.
Monica Yu (320718) +9 more
core +1 more source
International Journal of CancerAbstractBypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an important
Gábor Barna +4 more
openaire +2 more sources
Effect of Vitamin D on the Spleen of Adult Male Rats Fed on Diet with High Fat: A Histological and Immunohistochemical Study [PDF]
The Egyptian Journal of Histology, 2019 Background: High fat diet (HFD) is the cause of obesity prevalence which is a serious health problem. Vitamin D is considered a very important modulator in cellular inflammation and immune systems.Aim of the work: To demonstrate the histological changes ...
Heba Mohamed
doaj +1 more source
Cells, 2021 The kinetics of antigen-presenting cells (APCs) vary depending on their resident tissues and the manner of immunization. We investigated the long-term changes in mature APC and T-cell subsets over 4 weeks in the ocular surface in murine models of corneal
Kyoung-Woo Kim +3 more
doaj +1 more source