Results 41 to 50 of about 3,939 (188)
CD95/Fas ligand mRNA is toxic to cells
eLife, 2018 CD95/Fas ligand binds to the death receptor CD95 to induce apoptosis in sensitive cells. We previously reported that CD95L mRNA is enriched in sequences that, when converted to si/shRNAs, kill all cancer cells by targeting critical survival genes ...
Will Putzbach +8 more
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, 2023 International audienceTo better understand the stoichiometry of CD95L required to trigger apoptotic and nonapoptotic signals, we generated several CD95L concatemers from dimer to hexamer conjugated via a flexible link (GGGGS) .
Vacher, Pierre +15 more
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Markers of apoptosis in patients with type 1 diabetes mellitus at the onset of the disease
Сахарный диабет, 2009 Aim. This work was to study activation markers of apoptosis (CD95, CD95L) on peripheral blood lymphocytes of patients with type 1 diabetes mellitus (DM1) at the onset of the disease. Materials and methods.
Elena Vladimirovna Pekareva +6 more
doaj +1 more source
Majalah Kedokteran Bandung, 2022 Dengue is a disease caused by dengue virus (DENV) that is transmitted mainly by the female Aedes aegypti mosquito. There are four serotypes of DEN, leading to a possibility that a person may be infected four times by this virus, albeit with different ...
Nurfadly Nurfadly +2 more
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CD95L and Anti-Tumor Immune Response: Current Understanding and New Evidence
Cancer Management and Research, 2021 David M Richards, Christian Merz, Christian Gieffers, Andriy Krendyukov Apogenix AG, Heidelberg, GermanyCorrespondence: Andriy Krendyukov Tel +49 6221 5860877Email andriy.krendyukov@apogenix.comAbstract: The ability of FasL/CD95L to induce apoptosis in ...
Richards DM +3 more
doaj
Immunogenetic characteristics of LADA
Сахарный диабет, 2011 Latent autoimmune diabetes of adults (LADA) is a variant of autoimmune diabetes mellitus. Its clinical feature not typical for classical DM1 despitethe presence of positive autoantibodies is characterized by the low rate of autoimmune destruction that ...
Tatiana Vasil'evna Nikonova +7 more
doaj +1 more source
CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases
Frontiers in Immunology, 2017 Endothelial cells lining new blood vessels that develop during inflammatory disorders or cancers act as doors that either allow or block access to the tumor or inflamed organ.
Matthieu Le Gallo +10 more
doaj +1 more source
Molecular Pain, 2020 Objectives To explore the effects of trigeminal neuralgia on neurodegeneration in rats and the underlining mechanism. Methods Sixty adult male Sprague Dawley rats were divided randomly into Chronic Constriction Injury of the Rat’s Infraorbital Nerve (ION-
Lu Wang +6 more
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Bacteroides acidifaciens in the gut plays a protective role against CD95-mediated liver injury
Gut Microbes, 2022 The intestinal flora plays an important role in the development of many human and animal diseases. Microbiome association studies revealed the potential regulatory function of intestinal bacteria in many liver diseases, such as autoimmune hepatitis ...
Hesuiyuan Wang +18 more
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CD95 Structure, Aggregation and Cell Signaling
Frontiers in Cell and Developmental Biology, 2020 CD95 is a pre-ligand-associated transmembrane (TM) receptor. The interaction with its ligand CD95L brings to a next level its aggregation and triggers different signaling pathways, leading to cell motility, differentiation or cell death.
Nicolas Levoin +2 more
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