Cell-Free Nucleic Acids: Physico-Chemical Properties, Analytical Considerations, and Clinical Applications [PDF]
Diagnostics, 2023 Human body fluids are rich sources of cell-free nuclear material, which exhibits unique characteristics [...]
Abel J. Bronkhorst, Stefan Holdenrieder
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Circulating Cell-Free Nucleic Acids as Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer [PDF]
Biomedicines, 2023 A lack of reliable early diagnostic tools represents a major challenge in the management of pancreatic cancer (PCa), as the disease is often only identified after it reaches an advanced stage.
Anelis Maria Marin +5 more
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Circulating Cell-Free Nucleic Acids as Epigenetic Biomarkers in Precision Medicine [PDF]
Frontiers in Genetics, 2020 The circulating cell-free nucleic acids (ccfNAs) are a mixture of single- or double-stranded nucleic acids, released into the blood plasma/serum by different tissues via apoptosis, necrosis, and secretions. Under healthy conditions, ccfNAs originate from
Beenish Rahat +4 more
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Circulating cell-free nucleic acids of plasma in human aging, healthy aging and longevity: current state of knowledge [PDF]
Frontiers in Genetics, 2023 Circulating cell-free nucleic acids (ccfNAs) of plasma are a remarkable source of genetic, epigenetic and transcriptomic materials originating from different cells, tissues and organs of an individual.
Nicolas P. Tessier +4 more
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Breath biopsy biomarkers: cell-free nucleic acids in exhaled breath condensate [PDF]
Frontiers in MedicineExhaled breath condensate (EBC) has emerged as a promising, organ-specific biofluid for non-invasive molecular diagnostics. While breath analysis has traditionally focused on volatile organic compounds (VOCs), recent advances have shifted attention ...
Ondrej Pös +16 more
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Liquid Biopsy Frontiers in Pancreatic Cancer: Insights from Circulating Cell-Free Nucleic Acids [PDF]
CellsPancreatic cancer (PC) remains one of the most aggressive and lethal malignancies worldwide, largely due to late diagnosis, aggressive biology, limited therapeutic options and responsiveness.
Maria Latiano +11 more
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Cell-Free Nucleic Acids As Noninvasive Biomarkers For Colorectal Cancer Detection [PDF]
Frontiers in Genetics, 2014 Cell-free nucleic acids (CFNA) have been reported by several authors in blood, stool and urine of patients with colorectal cancer (CRC). These genetic biomarkers can be an indication of neoplastic colorectal epithelial cells, so they can potentially be ...
Hicham eMansour
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Cell-Free Nucleic Acids in Cardiovascular Disease: From Biomarkers to Mechanistic Drivers and Therapeutic Opportunities [PDF]
CellsCardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, with heart failure (HF) representing a major contributor to hospitalizations, healthcare costs, and death.
Hannah Morgan +10 more
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Liquid Biopsy as a Method for Minimally Invasive Diagnosis of Thyroid Cancer [PDF]
Клиническая практика, 2023 Thyroid cancer is the 9th most common cancer in the world. The five-year survival rate for this disease is over 98%. However, in some patients there are cases of rapidly progressive treatment-resistant cancer that cannot be differed from poor-invasive ...
Tagir I. Rakhmatullin +3 more
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mBio, 2023 Wall-less bacteria are broadly distributed in diverse habitats. They evolved from a common ancestor within the Firmicutes phylum through reductive evolution.
Rikuan Zheng +4 more
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