Results 11 to 20 of about 5,340,670 (292)

Cell-Penetrating Peptide–Bismuth Bicycles [PDF]

Angewandte Chemie, 2023
Cell-penetrating peptides (CPPs) play a significant role in the delivery of cargos into human cells for a wide range of therapeutic and diagnostic applications. We disclose the first CPPs based on peptide–bismuth bicycles, which can be readily obtained from commercially available peptide precursors, making them highly accessible for a wide range of ...
Saan Voss, Liam D. Adair, Katharina Achazi, Heeyoung Kim, Silke Bergemann, Ralf Bartenschlager, Elizabeth J. New, Jörg Rademann, Christoph Nitsche   +8 more
openaire   +4 more sources

Cell-Penetrating Peptides [PDF]

, 2011
Classes of Cell-Penetrating Peptides. Mechanisms of Cell Penetration, Interactions of Cell-Penetrating Peptides with Plasma Membranes and Lipid Models. Applications of Cell-Penetrating Peptides.
Langel, Ülo,, Mäger, Imre, Florén, Anders   +2 more
core   +4 more sources

Enhancing cellular uptake of activable cell-penetrating peptide–doxorubicin conjugate by enzymatic cleavage

International Journal of Nanomedicine, 2012
Nian-Qiu Shi, Wei Gao, Bai Xiang, Xian-Rong QiDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, People's Republic of ChinaAbstract: The use of activable cell-penetrating peptides (ACPPs) as molecular ...
Shi NQ, Gao W, Xiang B, Qi XR
doaj   +1 more source

Designed cell penetrating peptide dendrimers efficiently internalize cargo into cells [PDF]

, 2014
Redesigning linear cell penetrating peptides (CPPs) into a multi-branched topology with short dipeptide branches gave cell penetrating peptide dendrimers (CPPDs) with higher cell penetration, lower toxicity and hemolysis and higher serum stability than ...
Blattes, Emilyne, Kammer, Stephan M., Reymond, Jean-Louis, Eggimann, Gabriela A., Darbre, Tamis, Buschor, Stefanie, Biswas, Rasomoy   +6 more
core   +3 more sources

Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]

, 2011
Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van, Peter J. Sadler, Sadler, P. J., Hana Kostrhunova, Viktor Brabec, Brabec, V. (Viktor), Sabine H. van Rijt, Kostrhunova, Hana   +7 more
core   +1 more source

RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry. [PDF]

Cell
Perr J, Langen A, Almahayni K, Nestola G, Chai P, Lebedenko CG, Volk RF, Detrés D, Caldwell RM, Spiekermann M, Hemberger H, Bisaria N, Aiba T, Sánchez-Rivera FJ, Tzelepis K, Calo E, Möckl L, Zaro BW, Flynn RA.   +18 more
europepmc   +2 more sources

A novel CAV derived cell-penetrating peptide efficiently delivers exogenous molecules through caveolae-mediated endocytosis

Veterinary Research, 2018
Cell-penetrating peptide (CPP) is a promising cargo for delivering bioactive molecules. In this study, the N terminus of VP1 from chicken anemia virus, designated as CVP1, was found to carry enriched arginine residues with α-helix.
Gaowei Hu, Wenlv Zheng, Ao Li, Yaru Mu, Mingyu Shi, Tuofan Li, Haitao Zou, Hongxia Shao, Aijian Qin, Jianqiang Ye   +9 more
doaj   +1 more source

Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]

BioImpacts, 2015
Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari, Solmaz Maleki Dizaj, khosro adibkia   +2 more
doaj   +1 more source

Delivered complementation in planta (DCIP) enables measurement of peptide-mediated protein delivery efficiency in plants

Communications Biology, 2023
Using a fluorescence complementation assay, Delivered Complementation in Planta (DCIP), we demonstrate cell-penetrating peptide-mediated cytosolic delivery of peptides and recombinant proteins in Nicotiana benthamiana.
Jeffrey W. Wang, Henry J. Squire, Natalie S. Goh, Heyuan Michael Ni, Edward Lien, Cerise Wong, Eduardo González-Grandío, Markita P. Landry   +7 more
doaj   +1 more source

Designed Multifunctional Peptides for Intracellular Targets

Antibiotics, 2022
Nature’s way for bioactive peptides is to provide them with several related functions and the ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as penetratins, inspired the design of multifunctional constructs ...
Davor Juretić
doaj   +1 more source