The ciliary GTPase Arl13b regulates cell migration and cell cycle progression [PDF]
Acknowledgments We acknowledge Prof. Tamara Caspary from Emory University for kindly providing the cell lines, Linda Duncan from the University of Aberdeen Ian Fraser Cytometry Center for help with flow cytometry.
Clancy, Hannah +6 more
core +2 more sources
Targeting PKCθ promotes satellite cell self-renewal [PDF]
Skeletal muscle regeneration following injury depends on the ability of satellite cells (SCs) to proliferate, self-renew, and eventually differentiate. The factors that regulate the process of self-renewal are poorly understood. In this study we examined
Benedetti, Anna +4 more
core +1 more source
The distribution of cytoplasmic microtubules throughout the cell cycle of the centric diatom Stephanopyxis turris: their role in nuclear migration and positioning the mitotic spindle during cytokinesis. [PDF]
The cell cycle of the marine centric diatom Stephanopyxis turris consists of a series of spatially and temporally well-ordered events. We have used immunofluorescence microscopy to examine the role of cytoplasmic microtubules in these events.
Cande, WZ, McDonald, KL, Wordeman, L
core
The Evolutionary Reorganization of Ontogeny and Origin of Multicellularity [PDF]
The formation of morphogenetic mechanisms during emergence of multicellularity is discussed in this ...
Dovgal, I. V.
core +1 more source
No increase in radiation-induced chromosome aberration complexity detected by m-FISH after culture in the presence of 5’-bromodeoxyuridine [PDF]
The thymidine analogue, 5’-bromodeoxyuridine (BrdU), is a known mutagen that is routinely introduced into culture media for subsequent Harlequin stain analysis and determination of cell cycle status.
Anderson +38 more
core +1 more source
Multilevel regulation of RUVBL2 expression predicts poor prognosis in hepatocellular carcinoma
Background Hepatocellular carcinoma (HCC) is the second-most lethal cancer worldwide with a complex pathogenesis. RuvB-like 2 (RUVBL2) was previously found to contribute to hepatocarcinogenesis.
Tao Yan +6 more
doaj +1 more source
Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation [PDF]
Background: Breast cancer risk increases drastically in individuals carrying a germline BRCA1 mutation. The exposure to ionizing radiation for diagnostic or therapeutic purposes of BRCA1 mutation carriers is counterintuitive, since BRCA1 is active in the
A Pijpe +67 more
core +4 more sources
β-lactam antibiotics interfere with cross-linking of the bacterial cell wall, but the killing mechanism of this important class of antibiotics is not fully understood.
Camilla Jensen +11 more
doaj +1 more source
RAB family gene expression in breast cancer cells under influence of paclitaxel [PDF]
The aim of this study was to investigate the role of paclitaxel on RAB family of genes in primary breast cancer cell lines. The cancer breast cells obtained from 40 women during mastectomy were used to address this issue. The group included patients with
Andrzej Wilkolaski +3 more
core +1 more source
Collective and single cell behavior in epithelial contact inhibition [PDF]
Control of cell proliferation is a fundamental aspect of tissue physiology central to morphogenesis, wound healing and cancer. Although many of the molecular genetic factors are now known, the system level regulation of growth is still poorly understood.
A. Puliafito +42 more
core +4 more sources

