Spatial mechanisms of gene regulation in metazoan embryos [PDF]
, 1991 The basic characteristics of embryonic process throughout Metazoa are considered with focus on those aspects that provide insight into how cell specification occurs in the initial stages of development.
Davidson, Eric H.
core
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
NanomaterialsMultiplexed biosensing methods for simultaneously detecting multiple biomolecules are important for investigating biological mechanisms associated with physiological processes, developing applications in life sciences, and conducting medical tests.
Shangjie Zou, Guangdun Peng, Zhiqiang Ma
doaj +1 more source
Lineage-specific gene expression and the regulative capacities of the sea urchin embryo: a proposed mechanism [PDF]
, 1989 Three aspects of early sea urchin development are reviewed, and conclusions derived that lead to a unified concept of how the initial specifications of differential gene activity may occur in this embryo. i.
Davidson, Eric H.
core
Asymmetry tests for Bifurcating Auto-Regressive Processes with missing data
, 2011 We present symmetry tests for bifurcating autoregressive processes (BAR) when some data are missing. BAR processes typically model cell division data. Each cell can be of one of two types \emph{odd} or \emph{even}.
de Saporta, Benoîte +2 more
core +3 more sources
Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow +6 more
wiley +1 more source
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages [PDF]
, 2007 James A. Timmons +11 more
openalex +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Epigenetic reshaping through damage: promoting cell fate transition by BrdU and IdU incorporation
Cell & BioscienceBackground Thymidine analogs have long been recognized for their ability to randomly incorporate into DNA. However, the precise mechanisms through which thymidine analogs facilitate cell fate transition remains unclear.
Chuang Li +7 more
doaj +1 more source
Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair [PDF]
, 2002 Xinping Zhang +5 more
openalex +1 more source