Results 101 to 110 of about 3,540 (186)
The Male Mouse Meiotic Cilium Emanates from the Mother Centriole at Zygotene Prior to Centrosome Duplication [PDF]
, 2022 Pablo López‐Jiménez +5 more
openalex +1 more source
Biology Open, 2017 A small number of proteins form a conserved pathway of centriole duplication. In humans and flies, the binding of PLK4/Sak to STIL/Ana2 initiates daughter centriole assembly.
Matthew A. Cottee +3 more
doaj +1 more source
eLife, 2015 Centrioles are microtubule-based organelles crucial for cell division, sensing and motility. In Caenorhabditis elegans, the onset of centriole formation requires notably the proteins SAS-5 and SAS-6, which have functional equivalents across eukaryotic ...
Kacper B Rogala +8 more
doaj +1 more source
A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.
PLoS Biology, 2008 Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila cells to identify proteins required for centriole ...
Jeroen Dobbelaere +5 more
doaj +1 more source
Vesicular trafficking plays a role in centriole disengagement and duplication
Molecular Biology of the Cell, 2018 Centrosomes are the major microtubule-nucleating and microtubule-organizing centers of cells and play crucial roles in microtubule anchoring, organelle positioning, and ciliogenesis. At the centrosome core lies a tightly associated or “engaged” mother–daughter centriole pair.
Xie, Shuwei +9 more
openaire +2 more sources
Centriole assembly and the role of Mps1: defensible or dispensable?
Cell Division, 2011 The Mps1 protein kinase is an intriguing and controversial player in centriole assembly. Originally shown to control duplication of the budding yeast spindle pole body, Mps1 is present in eukaryotes from yeast to humans, the nematode C.
Fisk Harold A, Pike Amanda N
doaj +1 more source
Current biology : CB, 2001 Centriole duplication is a key step in the cell cycle whose mechanism is completely unknown. Why new centrioles always form next to preexisting ones is a fundamental question. The simplest model is that preexisting centrioles nucleate the assembly of new centrioles, and that although centrioles can in some cases form de novo without this nucleation ...
Marshall, Wallace F +2 more
openaire +2 more sources
Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors
Scientific Reports, 2019 Reproductive and respiratory organs, along with brain ventricles, are lined by multiciliated epithelial cells (MCC) that generate cilia-powered fluid flows.
Olivier Mercey +8 more
doaj +1 more source
Poc1B and Sas-6 Function Together during the Atypical Centriole Formation in Drosophila melanogaster
Cells, 2019 Insects and mammals have atypical centrioles in their sperm. However, it is unclear how these atypical centrioles form. Drosophila melanogaster sperm has one typical centriole called the giant centriole (GC) and one atypical centriole called the proximal
Kyoung H. Jo +5 more
doaj +1 more source
Cyclin-dependent kinase control of motile ciliogenesis
eLife, 2018 Cycling cells maintain centriole number at precisely two per cell in part by limiting their duplication to S phase under the control of the cell cycle machinery.
Eszter K Vladar +7 more
doaj +1 more source