Results 121 to 130 of about 3,996 (179)

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HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Shape And Copy Number Of Centriole Duplication

, 2016
Centrioles are microtubule-based, 9-fold symmetrical cylinder-like structures that duplicate exactly once per cell cycle. The 9-fold symmetry is defined by a geometric scaffold known as the cartwheel, upon which all centrioles are formed.
Kim, Minhee
core  

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors

Scientific Reports, 2019
Reproductive and respiratory organs, along with brain ventricles, are lined by multiciliated epithelial cells (MCC) that generate cilia-powered fluid flows.
Olivier Mercey, Adel Al Jord, Philippe Rostaing, Alexia Mahuzier, Aurélien Fortoul, Amélie-Rose Boudjema, Marion Faucourt, Nathalie Spassky, Alice Meunier   +8 more
doaj   +1 more source

Drosophila centrocortin is dispensable for centriole duplication but contributes to centrosome separation. [PDF]

G3 (Bethesda), 2022
Mehta DS, Zein-Sabatto H, Ryder PV, Lee J, Lerit DA.   +4 more
europepmc   +1 more source

Balancing the scales: fine-tuning Polo-like kinase 4 to ensure proper centriole duplication. [PDF]

Genes Dev, 2022
Ryniawec JM, Rogers GC.
europepmc   +1 more source

Upstream open reading frames control PLK4 translation and centriole duplication in primordial germ cells. [PDF]

Genes Dev, 2022
Phan TP, Boatwright CA, Drown CG, Skinner MW, Strong MA, Jordan PW, Holland AJ.   +6 more
europepmc   +1 more source

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. [PDF]

Commun Biol, 2021
Ho UY, Feng CA, Yeap YY, Bain AL, Wei Z, Shohayeb B, Reichelt ME, Homer H, Khanna KK, Bowles J, Ng DCH.   +10 more
europepmc   +1 more source

Autophosphorylation of Polo-like Kinase 4 and Its Role in Centriole Duplication

, 2010
Centrosome duplication occurs once every cell cycle in a strictly controlled manner. Polo-like kinase 4 (PLK4) is a key regulator of this process whose kinase activity is essential for centriole duplication. Here, we show that PLK4 autophosphorylation of
Nele Vloemans, Bonnet, Pascal, Michel Bornens, Tack, Frederik, Frans C. S. Ramaekers, Thierry Grand-perret, James E. Sillibourne, Vloemans, Nele, Frederik Tack, Thambirajah, Sathiesan, Grand-Perret, Thierry, Sathiesan Thambirajah, Sillibourne, James E., Pascal Bonnet, Boeckx, An, Bornens, Michel, Ramaekers, Frans C. S., An Boeckx   +17 more
core   +1 more source

The A-C linker controls centriole structural integrity and duplication

Nature Communications
Centrioles are evolutionarily conserved barrel-shaped organelles playing crucial roles in cell division and ciliogenesis. These functions are underpinned by specific structural sub-elements whose functions have been under investigation since many years.
Lorène Bournonville, Marine. H. Laporte, Susanne Borgers, Paul Guichard, Virginie Hamel   +4 more
openaire   +2 more sources

The Role of CEP120 and SPICE1 in Human Centriole Duplication

, 2015
The centrosome is a collection of proteins scaffolded upon microtubule based structures called centrioles. Centrosomes play critical roles as the primary microtubule organizing centers in interphase and mitotic cells, and template the formation of cilia
Comartin, David John
core   +1 more source