Results 111 to 120 of about 7,033 (216)

The effects of rosmarinic acid and carnosic acid on cell viability and ceramide metabolism in the HEP-G2 cells

open access: yesیافته‌های نوین در علوم زیستی, 2016
Carnosic acid and Rosmarinic acid are family of polyphenols that are found in Rosmary plant. They have property biological behaviors such as anti-cancer, anti-viral and anti-oxidants.
Narges Najjarpour   +1 more
doaj  

Human Acid Ceramidase [PDF]

open access: yesJournal of Biological Chemistry, 2001
Klaus Ferlinz   +9 more
openaire   +1 more source

Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity

open access: yesCommunications Biology
Two mammalian homologs of systemic RNA interference defective protein 1 (SID-1) (SIDT1/2) are suggested to function as double-stranded RNA (dsRNA) transporters for extracellular dsRNA uptake or for release of incorporated dsRNA from lysosome to cytoplasm.
Yoshinori Hirano   +5 more
doaj   +1 more source

Acid ceramidase-1 (ASAH1/aCDase) an important for anticancer drug discovery: a review

open access: yesFuture Journal of Pharmaceutical Sciences
Background Dysregulated sphingolipid metabolism has emerged as a major pathway in multiple human cancers. Sphingolipids are major structural components of cell membranes, playing key roles in maintaining structural integrity, fluidity, and barrier ...
Seemarani M. Pawar   +2 more
doaj   +1 more source

Acid Ceramidase in Melanoma [PDF]

open access: yesJournal of Biological Chemistry, 2016
Natalia Realini   +7 more
openaire   +1 more source

The Arabidopsis alkaline ceramidase ACER functions in defense against insect herbivory.

open access: yesJournal of Experimental Botany, 2022
Liqun Huang   +8 more
semanticscholar   +1 more source

P81 | AN IN VITRO CYTOTOXIC, PROAPOPTOTIC AND ANTITUMOR ACTIVITY ASSESSMENT FOR CERAMIDASE INHIBITORS ON HUMAN LARYNGEAL CANCER CELLS

open access: yesEuropean Journal of Histochemistry
Laryngeal cancer is diagnosed approximately 20% of head and neck cancers worldwide1. Among the potential sphingolipid-based treatment methods for the treatment of these fatal cancers2 acid ceramidase inhibition is indicated as a beneficial treatment ...
doaj   +1 more source

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