Results 51 to 60 of about 1,781 (177)
Generation of a ceramide synthase 6 mouse lacking the DDRSDIE C-terminal motif.
PLoS ONE, 2022 The important membrane lipid, ceramide, is generated by a family of homologous enzymes, the ceramide synthases (CerSs), multi-spanning membrane proteins located in the endoplasmic reticulum.
Jiyoon Kim +4 more
doaj +2 more sources
, 2021 Folic acid, an oxidized synthetic pro-vitamin B9, is widely used in vitamin supplement formulations and food fortification to maintain optimal folate status in humans. Studies on folic acid (FA) efficiency in improving folate status and correcting folate
Keri Barron (11652577) +2 more
core +1 more source
, 2021 Folic acid, an oxidized synthetic pro-vitamin B9, is widely used in vitamin supplement formulations and food fortification to maintain optimal folate status in humans. Studies on folic acid (FA) efficiency in improving folate status and correcting folate
Keri Barron (11652577) +2 more
core +1 more source
Journal of Lipid Research, 2011 Mammalian ceramide synthases 1 to 6 (CerS1–6) generate Cer in an acyl-CoA-dependent manner, and expression of individual CerS has been shown to enhance the synthesis of ceramides with particular acyl chain lengths.
Thomas D. Mullen +6 more
doaj +1 more source
iMetaMed, Volume 2, Issue 3, September 2026.Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo +4 more
wiley +1 more source
, 2021 Folic acid, an oxidized synthetic pro-vitamin B9, is widely used in vitamin supplement formulations and food fortification to maintain optimal folate status in humans. Studies on folic acid (FA) efficiency in improving folate status and correcting folate
Keri Barron (11652577) +2 more
core +1 more source
Molecular Plant Pathology, Volume 27, Issue 9, September 2026.Sphingolipid levels are elevated in CMV replication site (the tonoplast). Silencing Nb‐TSC10 activates the host salicylic acid–UPR defence axis, indicating CMV promotes sphingolipid biosynthesis to suppress this antiviral pathway. ABSTRACT RNA viruses usually reprogramme host cellular lipid metabolism to create favourable replication microenvironments,
Jiayi Yao +8 more
wiley +1 more source
CerS6 is a target of MTX in mediation of antiproliferative effect.
, 2016 (A) Silencing CerS6 by siRNA rescues A549 cells from cytotoxic effect of MTX while silencing CerS4 does not change the drug toxicity. Cells were transfected with scrambled siRNA, CerS6 siRNA or CerS4 siRNA (25 pmol), MTX was added 6 h later and live ...
Natalia I. Krupenko (439696) +3 more
core +1 more source
, 2021 Folic acid, an oxidized synthetic pro-vitamin B9, is widely used in vitamin supplement formulations and food fortification to maintain optimal folate status in humans. Studies on folic acid (FA) efficiency in improving folate status and correcting folate
Keri Barron (11652577) +2 more
core +1 more source
Advanced Science, Volume 13, Issue 44, 7 August 2026.This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu +5 more
wiley +1 more source