Results 191 to 200 of about 287,054 (305)

How conformational changes near the F pocket of MHC class I proteins mediate chaperone assisted peptide loading. [PDF]

Front Immunol
Göppert S, Springer S, Zacharias M.
europepmc   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Tuning the Hsp70 chaperone cycle: emerging roles of GrpE-like nucleotide exchange factors in proteostasis and organelle function. [PDF]

Protein Cell
Morizono MA, Safar TV, Herzik MA.
europepmc   +1 more source

Chaperone [PDF]

, 2018
openaire   +1 more source

Synergistic Impacts of Co‐Exposure to Microplastics and Vibrio harveyi on the Immune and Stress Responses of the Big‐Belly Seahorse Hippocampus abdominalis

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Synergistic effects of microplastic and Vibrio harveyi co‐exposure on big‐belly seahorse (Hippocampus abdominalis). Seahorses were exposed to microplastics (50 beads/L of 0.2 μm SMP and 1.0 μm LMP) and injected with V. harveyi (1 × 103 CFU/mL).
Jin A Kim, Min‐Min Jung, Seong Don Hwang, Jun‐Hwan Kim, Cheol Young Choi   +4 more
wiley   +1 more source

Targeting HSP90 in cancer: advances in the development of inhibitors, mechanisms of action, and therapeutic applications. [PDF]

Mol Cancer
Wang X, Ni R, Wang X, Li X.
europepmc   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori, Pedro Garcia Caparros, Antonella Castagna, Luisa Custódio, Valentina Lazazzara, Claus Krogh Madsen, Felicia Menicucci, Maria João Rodrigues, Katalin Solymosi, Jose Ramon Acosta Motos   +9 more
wiley   +1 more source

c-di-AMP-DasR signaling axis mediates mycobacterial acid resistance. [PDF]

mBio
Fu Y, Xie X-Q, Xu Z-H, Liang Y-F, Yang S-Q, Ye B-C, You D.   +6 more
europepmc   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

Recognition of small Tim chaperones by the mitochondrial Yme1 protease. [PDF]

Protein Sci
Quispe-Carbajal M, Todd L, Glynn SE.
europepmc   +1 more source