Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies. [PDF]
Perez Almeria CV +19 more
europepmc +1 more source
CCR2 improves tumor directed CAR-T cell trafficking in ovarian cancer. [PDF]
Kumar R +5 more
europepmc +1 more source
Multimodal Spatial Transcriptomics Reveals the Developing Human Liver Niche at Single-Cell Resolution. [PDF]
Bailey M, Leon M, Rosso I, Sangokoya C.
europepmc +1 more source
Chemokine Networks in Cutaneous T Cell Lymphoma: Tumor Microenvironment Remodeling and Therapeutic Targets. [PDF]
Yu Z +5 more
europepmc +1 more source
Identification of CXCL12 as a key gene of trophoblast and endometrial stromal cell decidualization in pregnancy via scRNA-seq and experimental validation. [PDF]
Sun X +5 more
europepmc +1 more source
A Breath of Fresh Insight: Targeting CXCR4 in Early Chronic Obstructive Pulmonary Disease. [PDF]
Bignold RE, Johnson JR.
europepmc +1 more source
CXCL12 Promotes Peripheral Nerve Injury Repair by Inhibiting the Ferroptosis-Inflammation Axis via the ERK/Nrf2 Pathway. [PDF]
Yuan Y +5 more
europepmc +1 more source
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Pathological roles of the homeostatic chemokine CXCL12
Cytokine & Growth Factor Reviews, 2018CXCL12 is a CXC chemokine that traditionally has been classified as a homeostatic chemokine. It contributes to physiological processes such as embryogenesis, hematopoiesis and angiogenesis. In contrast to these homeostatic functions, increased expression of CXCL12 in general, or of a specific CXCL12 splicing variant has been demonstrated in various ...
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The roles of chemokine CXCL12 in embryonic and brain tumor angiogenesis
Seminars in Cancer Biology, 2009The formation of blood vessels in embryos and tumors are different processes but under the control of common molecular mechanisms. Chemokine CXCL12 involved in both embryonic and tumor angiogenesis. In this review, we summarize recent advances in understanding the roles of CXCL12 in brain tumor angiogenesis/vasculogenesis.
Meizhang, Li, Richard M, Ransohoff
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