Results 11 to 20 of about 316,404 (122)

Studies on cholesterol 7α-Hydroxylase [PDF]

, 1976
Attempts were made to solubilize the enzyme cholesterol 7α-hydroxylase from native rat liver microsomes and from rat liver microsomal acetone and butanol powders.
Hattersley, Neil G.
core   +3 more sources

Comparison of Cholesterol Lowering Diets: Apple, Casein Cytochrom P450 protein and Cholesterol 7α Hydroxylase Activities in Hamsters [PDF]

, 2010
Lithogenic diet, casein and apple fiber diets were fed to hamsters for 3-5 weeks. For control group, animals were fed on normal Purina chow without any supplement.
Rakesh Sharma, Rakesh K. Tandon, Rakesh Sharma, Rakesh Tandon   +3 more
core   +1 more source

Heterogeneous expression of cholesterol 7α-hydroxylase and sterol 27- hydroxylase genes in the rat liver lobulus [PDF]

, 1995
We investigated the lobular localization and molecular level of expression of cholesterol 7α-hydroxylase and sterol 27-hydroxylase, two key enzymes in bile acid synthesis, in isolated periportal and pericentral hepatocytes and by in situ hybridization of
Moorman, A.F.M., Twisk, J.W.R., M F Hoekman, Gebhardt, R., A F Moorman, H M Princen, Sheja, L., Twisk, J., W H Mager, J Twisk, Scheja, L., Moorman, A. F., Boer, P.A.J. de, L Scheja, de Boer, P. A., Princen, H. M., R Gebhardt, Mager, W. H., Mager, W.H., Hoekman, M. F., Princen, H.M.G., de Boer, P.A.J., Hoekman, M.F.M., P A de Boer, Gebhart, R.   +24 more
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Differences in mechanisms of modulation between rat liver cholesterol 7α-hydroxylase and HMG-CoA reductase [PDF]

, 1985
The effects of microsomal HMG-CoA reductase kinase, cytosolic phosphoprotein phosphatase and cytosolic, thiol-dependent cholesterol 7α-hydroxylase stimulatory protein on purified cholesterol 7α-hydroxylase and HMG-CoA reductase from rat liver were ...
Bodil Lidström-Olsson, Lidström-Olsson, Bodil   +1 more
core   +1 more source

Molecular cloning of cDNA for cholesterol 7α-hydroxylase from rat liver microsomes Nucleotide sequence and expression [PDF]

, 1989
A complete cDNA clone encoding cholesterol 7α-hydroxylase was isolated from a rat liver cDNA library by the use of specific antibodies to the enzyme. The isolated cDNA clone was 3.6 kbp long and contained a 1509-bp open reading frame encoding 503 amino ...
Okuda, Kyuichiro, Masazumi Nishimoto, Kyuichiro Okuda, Noshiro, Mitsuhide, Mitsuhide Noshiro, Nishimoto, Masazumi, Ken-ichirou Morohashi, Morohashi, Ken-ichirou   +7 more
core   +1 more source

Structure and functions of human oxysterol 7α-hydroxylase cDNAs and gene CYP7B1

Journal of Lipid Research, 1999
Oxysterol 7α-hydroxylase has broad substrate specificity for sterol metabolites and may be involved in many metabolic processes including bile acid synthesis and neurosteroid metabolism.
Zhengliang Wu, K.O. Martin, N.B. Javitt, J.Y.L. Chiang   +3 more
doaj   +1 more source

Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription

Journal of Lipid Research, 2000
Fibrates are widely used hypolipidemic drugs that regulate the expression of many genes involved in lipid metabolism by activating the peroxisome proliferator-activated receptor α (PPARα).
Maria Marrapodi, John Y.L. Chiang
doaj   +1 more source

Studies on the formation of C7-oxygenated cholesterol and β-sitosterol metabolites in cell-free preparations of rat liver

Journal of Lipid Research, 1973
The microsomal fraction and the 18,000 g supernatant fluid obtained from livers from normal rats, cholestyraminetreated rats, or from rats with a bile fistula have been used to compare the 7α-hydroxylation of [4-14C]cholesterol and β-[4-14C]sitosterol ...
Leif Aringer, Peter Eneroth
doaj   +1 more source

Short- and long-term effects of ethanol administration in vivo on rat liver HMG-CoA reductase and cholesterol 7α-hydroxylase activities

Journal of Lipid Research, 1977
Short- and long-term effects of ethanol on HMG-CoA reductase (EC 1.1.1.34) and cholesterol 7α-hydroxylase activities in rat liver have been investigated.
M R Lakshmanan, R L Veech
doaj   +1 more source

Cholecystectomy prevents expansion of the bile acid pool and inhibition of cholesterol 7α-hydroxylase in rabbits fed cholesterol

Journal of Lipid Research, 2001
To study the effect of cholecystectomy on the regulation of classic and alternative bile acid syntheses, gallbladder-intact (n = 20) and cholecystectomized (n = 20) New Zealand White rabbits were fed either chow or chow with 2% cholesterol (3 g/day ...
Guorong Xu, Gerald Salen, Benjamin L. Shneider, M. Ananthanarayanan, Sarah Shefer, Lin Ma, Ashok Batta, Lien B. Nguyen, Josephine J. Lingutla, G. Stephen Tint, Mark Pcolinsky, Frederick J. Suchy   +11 more
doaj   +1 more source