Results 31 to 40 of about 5,987 (179)
Phospholipids modify substrate binding and enzyme activity of human cytochrome P450 27A1
Journal of Lipid Research, 2004 Cytochrome P450 27A1 (P450 27A1) is an important metabolic enzyme involved in bile acid biosynthesis and the activation of vitamin D3 in mammals.
Dilyara A. Murtazina +5 more
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Stimulation of cholesterol 7α-hydroxylase by phenobarbital in two strains of rats
Journal of Lipid Research, 1972 The effect of phenobarbital administration on the in vitro activity of cholesterol 7α-hydroxylase was investigated in two strains of rats. In rats of the Wistar strain the daily injection of phenobarbital (100 mg/kg per day ip for 5 days) produced a 33 ...
S. Shefer, S. Hauser, E.H. Mosbach
doaj +1 more source
iScience, 2020 Summary: Neuroactive steroids, termed neurosteroids, are synthesized locally in the brain and influence biological functions including cognition and behavior.
Kanako Maehata +8 more
doaj +1 more source
, 2010 Lithogenic diet, casein and apple fiber diets were fed to hamsters for 3-5 weeks. For control group, animals were fed on normal Purina chow without any supplement.
Rakesh Sharma +3 more
core +1 more source
Journal of Lipid Research, 1976 Cholesterol 7α-hydroxylase activity was assayed in liver microsomes from guinea pigs supplemented with ascorbate and from guinea pigs in a state of ascorbate deficiency.
I Björkhem, A Kallner
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On the heterogeneity of the mitochondrial C27-steroid 26-hydroxylase system
Journal of Lipid Research, 1976 Mitochondrial 26-hydroxylation of exogenous cholesterol, endogenous cholesterol, and 5β-cholestane-3α,7α,12α-triol was studied. 26-Hydroxylation of endogenous cholesterol was measured by mass fragmentography.
J Gustafsson
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, 1985 The effects of microsomal HMG-CoA reductase kinase, cytosolic phosphoprotein phosphatase and cytosolic, thiol-dependent cholesterol 7α-hydroxylase stimulatory protein on purified cholesterol 7α-hydroxylase and HMG-CoA reductase from rat liver were ...
Bodil Lidström-Olsson +1 more
core +1 more source
, 1989 A complete cDNA clone encoding cholesterol 7α-hydroxylase was isolated from a rat liver cDNA library by the use of specific antibodies to the enzyme. The isolated cDNA clone was 3.6 kbp long and contained a 1509-bp open reading frame encoding 503 amino ...
Okuda, Kyuichiro +7 more
core +1 more source
The use of [7α-3H]- and [7α, 7β-3H]cholesterol in the enzymic assay of cholesterol 7α-hydroxylase
Journal of Lipid Research, 1976 A tritium release method is described for following the enzymic conversion of cholesterol to 7α-hydroxycholesterol. Incubations of rat liver subcellular preparations (containing microsomes) with [7α-3H]cholesterol or [7α,7β-3H]cholesterol release the ...
D B Johnson, M P Tyor, L Lack
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Determination of hepatic cholesterol 7α-hydroxylase activity in man
Journal of Lipid Research, 1974 Methods were developed to determine the activity of the microsomal enzyme cholesterol 7α-hydroxylase in human liver. The enzyme assay could be performed with as little as 20 mg of fresh liver tissue, thus making the procedure applicable to specimens ...
G. Nicolau +3 more
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