Results 11 to 20 of about 50,002 (295)

Cholesterol efflux and reverse cholesterol transport [PDF]

, 2014
Both alterations of lipid/lipoprotein metabolism and inflammatory events contribute to the formation of the atherosclerotic plaque, characterized by the accumulation of abnormal amounts of cholesterol and macrophages in the artery wall.
FAVARI, Elda, ZANOTTI, Ilaria, Chroni, Angeliki, Escolà-Gil, Joan Carles, Uwe J. F. Tietge, Elda Favari, Joan Carles Escolà-Gil, BERNINI, Franco, Franco Bernini, Ilaria Zanotti, Tietge, Uwe J. F, Universitat Autònoma de Barcelona, Escolà Gil, Joan Carles, Tietge, Uwe J.F., Chroni, Angelika, Angelika Chroni   +15 more
core   +6 more sources

Cholesterol efflux capacity.

Journal of the American College of Cardiology, 2016
Apolipoprotein B (apoB)-depleted sera of healthy subjects (control, n = 27) and patients with age-related macular degeneration (AMD, n = 29) were examined for (A) their ability to promote [3H]-cholesterol efflux from macrophages. [3H]-cholesterol-labeled
Anton Haas (420487), Silke Hausberger (755976), Sabine Kern (3171669), Markus Trieb (3171666), Hubert Scharnagl (435522), Gunther Marsche (312903), Akos Heinemann (142582), Laura Pertl (755975), Vanessa Gasser-Steiner (3171672), Martin Weger (403811)   +9 more
core   +2 more sources

Cholesterol efflux pathways, inflammation, and atherosclerosis [PDF]

Critical Reviews in Biochemistry and Molecular Biology, 2021
Plasma levels of high-density lipoprotein (HDL) inversely correlate with the incidence of cardiovascular diseases (CVD). The causal relationship between plasma HDL-cholesterol levels and CVD has been called into question by Mendelian randomization ...
Tall, Alan R., Halmos, Benedek, Groenen, Anouk G., Groenen, Anouk G.; id_orcid, Halmos, Benedek; id_orcid, Westerterp, Marit; id_orcid, Westerterp, Marit   +6 more
core   +4 more sources

Transintestinal cholesterol efflux

Current Opinion in Lipidology, 2010
Purpose of review Regulation of cholesterol homeostasis is a complex interplay of a multitude of metabolic pathways situated in different organs. The liver plays a central role and has received most attention of the research community. In this review, we
Brufau, Gemma, Groen, Albert K., van der Velde, Astrid E.   +2 more
core   +6 more sources

Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1s⃞ [PDF]

Journal of Lipid Research, 2007
ABCG1, one of the half-type ATP binding cassette (ABC) proteins, mediates the efflux of cholesterol to HDL and functions in the reverse cholesterol transport from peripheral cells to the liver.
Osamu Sano, Aya Kobayashi, Kohjiro Nagao, Keigo Kumagai, Noriyuki Kioka, Kentaro Hanada, Kazumitsu Ueda, Michinori Matsuo   +7 more
doaj   +3 more sources

Sesamin Enhances Cholesterol Efflux in RAW264.7 Macrophages [PDF]

Molecules, 2014
Foam cells formation as a result of the uncontrolled cytophagy of modified cholesterol by macrophages plays a key role in the occurrence and development of atherosclerosis.
Lizhong Sun, Chongming Wu, Nan Liu, Jun Zheng, Peng Guo   +4 more
core   +4 more sources

Cholesterol Efflux Assay [PDF]

Journal of Visualized Experiments, 2012
Cholesterol content of cells must be maintained within the very tight limits, too much or too little cholesterol in a cell results in disruption of cellular membranes, apoptosis and necrosis. Cells can source cholesterol from intracellular synthesis and from plasma lipoproteins, both sources are sufficient to fully satisfy cells' requirements for ...
Hann, Low, Anh, Hoang, Dmitri, Sviridov
openaire   +2 more sources

Cholesterol efflux [PDF]

Arteriosclerosis thrombosis and vascular biology, 2012
Monocytosis and neutrophilia are well-established risk factors for atherosclerosis and seem to play a causative role in lesion development. Studies in mice with defects in cholesterol efflux pathways have identified novel roles for the ATP-binding cassette transporter A1, ATP-binding cassette transporter G1, and apolipoprotein E in suppressing ...
Tall, Alan R, Yvan-Charvet, Laurent, Westerterp, Marit, Murphy, Andrew J   +3 more
openaire   +3 more sources

Targeted cholesterol efflux [PDF]

Cell Cycle, 2013
In the process of reverse cholesterol transport, high-density lipoprotein (HDL) transports excess cholesterol from peripheral cells back to the liver, where cholesterol is recycled or metabolized and excreted. On the cellular level, 2 membrane-associated ATP-binding cassette (ABC) cholesterol transporters, ABCA1 and ABCG1, play a major role in ...
Fang, Longhou, Miller, Yury I
openaire   +2 more sources

Reverse cholesterol transport and cholesterol efflux in atherosclerosis [PDF]

QJM: An International Journal of Medicine, 2005
Reverse cholesterol transport (RCT) is a pathway by which accumulated cholesterol is transported from the vessel wall to the liver for excretion, thus preventing atherosclerosis. Major constituents of RCT include acceptors such as high-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I), and enzymes such as lecithin:cholesterol acyltransferase ...
R, Ohashi, H, Mu, X, Wang, Q, Yao, C, Chen   +4 more
openaire   +2 more sources