Results 1 to 10 of about 201,890 (354)

Chromatin remodeling in oligodendrogenesis

open access: yesВавиловский журнал генетики и селекции, 2021
Oligodendrocytes are one type of glial cells responsible for myelination and providing trophic support for axons in the central nervous system of vertebrates.
E. V. Antontseva, N. P. Bondar
doaj   +4 more sources

Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement [PDF]

open access: yeseLife, 2019
Eukaryotic DNA is packaged into nucleosome arrays, which are repositioned by chromatin remodeling complexes to control DNA accessibility. The Saccharomyces cerevisiae RSC (Remodeling the Structure of Chromatin) complex, a member of the SWI/SNF chromatin ...
Avinash B Patel   +6 more
doaj   +5 more sources

Chromatin remodeling complexes: architects influencing breast cancer progression [PDF]

open access: yesFrontiers in Cell and Developmental Biology
As one of the most common types of cancer, breast cancer strongly contributes to the increase in morbidity and mortality worldwide. Alterations in the genetic and epigenetic landscape contribute to the complexity and heterogeneity of the disease, making ...
Octavianus Giovani   +3 more
doaj   +2 more sources

Endothelial cells retain inflammatory memory through chromatin remodeling in a two-hit model of infection-induced inflammation. [PDF]

open access: hybridAm J Physiol Cell Physiol
Gonsales Spindola D   +15 more
europepmc   +2 more sources

Chromatin-Remodeling Factor BRG1 Is a Negative Modulator of L. donovani in IFNγ Stimulated and Infected THP-1 Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Intracellular pathogens manipulate the host cell for their own survival by contributing to modifications of host epigenome, and thus, altering expression of genes involved in the pathogenesis.
Harsimran Kaur Brar   +5 more
doaj   +1 more source

The Current Therapeutic Role of Chromatin Remodeling for the Prognosis and Treatment of Heart Failure

open access: yesBiomedicines, 2023
Cardiovascular diseases are a major cause of death globally, with no cure to date. Many interventions have been studied and suggested, of which epigenetics and chromatin remodeling have been the most promising.
Lindsay Kraus, Brianna Beavens
doaj   +1 more source

The chromatin remodeler SPLAYED regulates specific stress signaling pathways. [PDF]

open access: yesPLoS Pathogens, 2008
Organisms are continuously exposed to a myriad of environmental stresses. Central to an organism's survival is the ability to mount a robust transcriptional response to the imposed stress. An emerging mechanism of transcriptional control involves dynamic
Justin W Walley   +6 more
doaj   +1 more source

Small molecule modulators of chromatin remodeling: from neurodevelopment to neurodegeneration

open access: yesCell & Bioscience, 2023
The dynamic changes in chromatin conformation alter the organization and structure of the genome and further regulate gene transcription. Basically, the chromatin structure is controlled by reversible, enzyme-catalyzed covalent modifications to chromatin
Dongfang Jiang   +4 more
doaj   +1 more source

Knockdown of DOM/Tip60 Complex Subunits Impairs Male Meiosis of Drosophila melanogaster

open access: yesCells, 2023
ATP-dependent chromatin remodeling complexes are involved in nucleosome sliding and eviction and/or the incorporation of histone variants into chromatin to facilitate several cellular and biological processes, including DNA transcription, replication and
Yuri Prozzillo   +5 more
doaj   +1 more source

Sodium Valproate-Induced Chromatin Remodeling

open access: yesFrontiers in Cell and Developmental Biology, 2021
Valproic acid/sodium valproate (VPA), a drug originally prescribed as an anticonvulsant, has been widely reported to act on epigenetic marks by inducing histone acetylation, affecting the DNA and histone methylation status, and altering the expression of
Maria Luiza S. Mello
doaj   +1 more source

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