Results 91 to 100 of about 45,661 (289)
Target RNAs strike back on MicroRNAs [PDF]
, 2018 MicroRNAs are extensively studied regulatory non-coding small RNAs that silence animal genes throughout most biological processes, typically doing so by binding to partially complementary sequences within target RNAs.
de la Mata, Manuel +3 more
core +1 more source
Autophagy-associated circRNA circCDYL augments autophagy and promotes breast cancer progression
Molecular Cancer, 2020 Although both circular RNAs (circRNAs) and autophagy are associated with the function of breast cancer (BC), whether circRNAs regulate BC progression via autophagy remains unknown.
G. Liang +17 more
semanticscholar +1 more source
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Advanced Materials, EarlyView.Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
, 2023 Creative Biogene is a global biotechnology company devoting to offer high-quality service for customers. We provide a one stop solution for circRNA prediction, identification, preliminary screening, functional analysis and circRNA-miRNA/RBP interaction mechanism analysis to accelerate your biomarker discovery and drug development research. Supported by
openaire +2 more sources
CircRNAs in cancer metabolism: a review [PDF]
Journal of Hematology & Oncology, 2019 Altered energy metabolism is a hallmark of tumors aiming at supplying necessary nutrients for tumorigenesis and development. These redirected metabolic pathways associated with carbohydrate, lipid and amino acid are orchestrated not only by carcinogenic proteins but by non-coding RNAs.
Tao Yu +6 more
openaire +4 more sources
Roles of circRNAs in the tumour microenvironment [PDF]
Molecular Cancer, 2020 AbstractThe tumour microenvironment (TME) constitutes the area surrounding the tumour during its development and has been demonstrated to play roles in cancer-related diseases through crosstalk with tumour cells. Circular RNAs (circRNAs) are a subpopulation of endogenous noncoding RNAs (ncRNAs) that are ubiquitously expressed in eukaryotes and have ...
Qiuge Zhang +7 more
openaire +4 more sources
Open Medicine, 2023 The aim of this study is to explore the prognostic value of vascular invasion (VI) in hepatocellular carcinoma (HCC) by searching for competing endogenous RNAs (ceRNA) network and constructing a new prognostic model for HCC.
Liu Yun +6 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the expression of hsa_circ_0018574 in colorectal cancer tissues and human colon cancer HT29 cell line, as well as its effect on the proliferation and apoptosis of colorectal cancer cells.
MA Rui +5 more
doaj +1 more source
The Ins and Outs of miRNA-Mediated Gene Silencing during Neuronal Synaptic Plasticity [PDF]
, 2016 Neuronal connections through specialized junctions, known as synapses, create circuits that underlie brain function. Synaptic plasticity, i.e., structural and functional changes to synapses, occurs in response to neuronal activity and is a critical ...
Hanley, Jonathan, Rajgor, Dipen
core +2 more sources
The circular RNA landscape in multiple sclerosis: Disease-specific associated variants and exon methylation shape circular RNA expression profile [PDF]
, 2023 BACKGROUND: Circular RNAs (circRNAs) are a class of non-coding RNAs increasingly emerging as crucial actors in the pathogenesis of human diseases, including autoimmune and neurological disorders as multiple sclerosis (MS).
Airi, Federica +14 more
core +3 more sources