Results 111 to 120 of about 52,173 (326)
Emerging Concepts and Challenges in Rheumatoid Arthritis Gene Therapy
Biomedicines, 2020 Rheumatoid arthritis (RA) is a systemic inflammatory joint disease affecting about 1% of the population worldwide. Current treatment approaches do not ensure a cure for every patient.
Andrei A. Deviatkin +6 more
doaj +1 more source
Comprehensive analysis of circRNA expression profiles in rat cerebral cortex after moderate traumatic brain injury [PDF]
, 2022 Gang Li +5 more
openalex +1 more source
Circbank: a comprehensive database for circRNA with standard nomenclature
RNA Biology, 2019 Circular RNAs (circRNAs) represent a new type of regulatory RNA which forms a covalently closed continuous loop from back-splicing events, a process in which the downstream 5′ splice site and the 3′ splice site are covalently linked.
Ming Liu +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li +10 more
wiley +1 more source
CircRNAs and Fusion-circRNAs in cancer: New players in an old game
Cellular Signalling, 2020 Circular RNAs (circRNAs) are generated from 'back-splicing' events. Their circular structure makes them stable in cells and body fluids. These entities are involved in several human diseases including cancer, as they affect the expression of genes promoting proliferation, invasion, apoptosis, and angiogenesis.
Grazia Visci +5 more
openaire +3 more sources
International Journal of General Medicine, 2023 Lianbo Hu,1 Bingrong Zheng,2 Yang Yang,2 Chunmei Chen,2 Meiwei Hu2 1Physical Examination Center, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Hu L, Zheng B, Yang Y, Chen C, Hu M
doaj
The Recent Research Progress of CircRNA in Bladder Cancer
Annals of Urologic Oncology, 2023 Bladder cancer is a major public health problem in the world, and is one of the most common malignant tumors in the genito-urinary system. Due to its high incidence and mortality, it remains a serious threat to human health.
Shuo Liu, Xin-liang Xu
doaj +1 more source
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes. [PDF]
, 2017 RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA composition of EVs is challenging due to their coisolation with contaminants, lack of knowledge of the mechanisms of RNA sorting into EVs, and limitations of ...
Lambowitz, Alan M +6 more
core +1 more source
Regulatory Role of circRNA-0067835 in Behcet Disease through Targeting Micro RNA-155: Implication of ATG1, AKT and MTOR. [PDF]
, 2023 Shimaa Saad El‐Din +5 more
openalex +1 more source
Molecular Medicine Reports, 2021 Atherosclerosis (AS) is a chronic inflammatory disease of the vascular wall with multiple causes. AS is the primary pathological basis of cardiovascular disease and stroke.
Y. Wen +10 more
semanticscholar +1 more source