Results 31 to 40 of about 45,661 (289)
Journal of experimental & clinical cancer research : CR, 2023 Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back-splicing. CircRNAs are abnormally expressed in many tumors, and play critical roles in
Jianxia Wei +10 more
semanticscholar +1 more source
Characterizing viral circRNAs and their application in identifying circRNAs in viruses
Briefings in Bioinformatics, 2021 Abstract Circular RNAs (circRNAs) are non-coding RNAs with a special circular structure produced formed by the reverse splicing mechanism, which play an important role in a variety of biological activities. Viruses can encode circRNA, and viral circRNAs have been found in multiple single-stranded and double-stranded viruses. However, the
Mengting Niu +3 more
openaire +3 more sources
口腔疾病防治, 2020 Objective To explore the effect of circ_0001273 on the proliferation, migration and invasion of oral squamous cell carcinoma（OSCC） cells and to provide a relevant research basis for the use of targeted therapy in OSCC.
ZENG Fantao, YU Dongsheng
doaj +1 more source
LncRNA and circRNA in Patients with Non-Alcoholic Fatty Liver Disease: A Systematic Review
Biomolecules, 2023 Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease worldwide. Early identification and prompt treatment are critical to optimize patient management and improve long-term prognosis.
Q. Zeng +5 more
semanticscholar +1 more source
RNA Biology, 2016 Circular RNAs (circRNAs) are highly abundant and evolutionarily conserved non-coding RNAs produced by circularization of specific exons. Since their re-discovery as potential regulators of gene expression, thousands of circRNAs were detected in different tissues and cell types across most organisms.
Sebastian Kadener +2 more
openaire +2 more sources
CircRNAs in Tumor Radioresistance
Biomolecules, 2022 Circular RNAs (circRNAs) are endogenous, non-coding RNAs, which are derived from host genes that are present in several species and can be involved in the progression of various diseases. circRNAs’ leading role is to act as RNA sponges. In recent years, the other roles of circRNAs have been discovered, such as regulating transcription and translation ...
Yining Gao +7 more
openaire +3 more sources
Unveiling Circular RNA-Mediated Regulatory Mechanisms in Necroptosis in Premature Ovarian Failure
Frontiers in Bioscience-Landmark, 2023 Background: Necroptosis is a programmed necrotic cell death, in which dying cells rupture and release intracellular components that trigger a proinflammatory response.
Xin Jin +6 more
doaj +1 more source
Nature Reviews Molecular Cell Biology, 2020 Increased expression of the circular RNA generated by the sulfateless gene (circSfl), and of the protein it encodes, can extend the lifespan of flies.
openaire +2 more sources
CircRNA expression profile and circRNA-miRNA-mRNA crosstalk in allergic rhinitis [PDF]
World Allergy Organization Journal, 2020 Circular RNAs (circRNAs) are involved in inflammation; however, their role in allergic rhinitis (AR) remains unclear. In this study, we analyzed circRNA expression and identified a circRNA-miRNA-mRNA network through which circRNAs regulate AR pathogenesis.We analyzed circRNA, miRNA, and mRNA expression profiles in the nasal mucosa by high-throughput ...
Chang-Yu Qiu +7 more
openaire +5 more sources
Circular RNA–MicroRNA–MRNA interaction predictions in SARS-CoV-2 infection
Journal of Integrative Bioinformatics, 2021 Different types of noncoding RNAs like microRNAs (miRNAs) and circular RNAs (circRNAs) have been shown to take part in various cellular processes including post-transcriptional gene regulation during infection.
Demirci Yılmaz Mehmet +1 more
doaj +1 more source