Results 41 to 50 of about 52,173 (326)

CircRNAs in Tumor Radioresistance

Biomolecules, 2022
Circular RNAs (circRNAs) are endogenous, non-coding RNAs, which are derived from host genes that are present in several species and can be involved in the progression of various diseases. circRNAs’ leading role is to act as RNA sponges. In recent years, the other roles of circRNAs have been discovered, such as regulating transcription and translation ...
Yining Gao, Jiawen Gao, Fei Lin, Ting Wang, Sitong Huo, Jiefang Wu, Qi Zhou, Chao Zhang   +7 more
openaire   +3 more sources

Combined exposure to noise and CO induces adverse male reproductive effects in rats

陆军军医大学学报, 2023
Objective To explore the male reproductive toxicity in rats caused by single or combined exposure to noise and carbon monoxide (CO) in closed cabin, and evaluate the joint effects and associated signal pathways.
LI Yingqing, LIU Chang, ZHANG Zhonghao, WANG Jiankang, SUN Lei   +4 more
doaj   +1 more source

Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression

Journal of experimental & clinical cancer research : CR, 2023
Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back-splicing. CircRNAs are abnormally expressed in many tumors, and play critical roles in
Jianxia Wei, Mengna Li, Changning Xue, Shipeng Chen, Lemei Zheng, H. Deng, Faqing Tang, Gui-yuan Li, Wei Xiong, Zhaoyang Zeng, M. Zhou   +10 more
semanticscholar   +1 more source

Circular RNA–MicroRNA–MRNA interaction predictions in SARS-CoV-2 infection

Journal of Integrative Bioinformatics, 2021
Different types of noncoding RNAs like microRNAs (miRNAs) and circular RNAs (circRNAs) have been shown to take part in various cellular processes including post-transcriptional gene regulation during infection.
Demirci Yılmaz Mehmet, Saçar Demirci Müşerref Duygu   +1 more
doaj   +1 more source

Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

Molecular Cancer, 2020
Non-coding RNAs do not encode proteins and regulate various oncological processes. They are also important potential cancer diagnostic and prognostic biomarkers.
Pan Wu, Yongzhen Mo, M. Peng, T. Tang, Y. Zhong, Xiangying Deng, F. Xiong, Can Guo, Xu Wu, Yong Li, Xiaoling Li, Gui-yuan Li, Zhaoyang Zeng, W. Xiong   +13 more
semanticscholar   +1 more source

Intergenic CircRNA Circ_0007379 Inhibits Colorectal Cancer Progression by Modulating miR-320a Biogenesis in a KSRP-Dependent Manner

International Journal on Biological Sciences, 2023
Circular RNAs (circRNAs) are covalently closed RNA structures that play multiple roles in tumorigenesis and progression. Compared with exon‒intron circRNAs, the biological functions and implications of intergenic circRNAs in human cancer are still poorly
Fei Long, Liang Li, Canbin Xie, M. Ma, Zhi-feng Wu, Zhixin Lu, Baiying Liu, Ming Yang, Fan Zhang, Zhengping Ning, Chonglei Zhong, Bowen Yu, Shiyi Liu, Longyu Wan, Buning Tian, Kaiyan Yang, Yihang Guo, Miao Chen, Jing Chou, Xiaorong Li, G. Hu, Changwei Lin, Yi Zhang   +22 more
semanticscholar   +1 more source

Expression of Circular RNA hsa_circ_0018574 in Colorectal Cancer Tissues and Its Effect on Proliferation of Colorectal Cancer Cells

Zhongliu Fangzhi Yanjiu, 2022
Objective To investigate the expression of hsa_circ_0018574 in colorectal cancer tissues and human colon cancer HT29 cell line, as well as its effect on the proliferation and apoptosis of colorectal cancer cells.
MA Rui, TIAN Jinhai, MA Rong, WAN Qiaofeng, LIU Hetao, WANG Libin   +5 more
doaj   +1 more source

LncRNA and circRNA in Patients with Non-Alcoholic Fatty Liver Disease: A Systematic Review

Biomolecules, 2023
Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease worldwide. Early identification and prompt treatment are critical to optimize patient management and improve long-term prognosis.
Q. Zeng, Chang-Hai Liu, Dongbo Wu, Wei Jiang, Nan Zhang, Hong Tang   +5 more
semanticscholar   +1 more source

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons [PDF]

, 2017
The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Bozzoni, Irene, Caffarelli, Elisa, Capauto, Davide, Colantoni, Alessio, DE SANTIS, Riccardo, DINI MODIGLIANI, Stefano, Errichelli, Lorenzo, Laneve, Pietro, Legnini, Ivano, Lu, Lei, Morlando, Mariangela, Peruzzi, Giovanna, Rosa, Alessandro, Scarfò, Rebecca, Shneider, Neil A.   +14 more
core   +1 more source

Characterizing viral circRNAs and their application in identifying circRNAs in viruses

Briefings in Bioinformatics, 2021
Abstract Circular RNAs (circRNAs) are non-coding RNAs with a special circular structure produced formed by the reverse splicing mechanism, which play an important role in a variety of biological activities. Viruses can encode circRNA, and viral circRNAs have been found in multiple single-stranded and double-stranded viruses. However, the
Mengting Niu, Ying Ju, Chen Lin, Quan Zou   +3 more
openaire   +2 more sources