Results 51 to 60 of about 45,661 (289)
FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons [PDF]
, 2017 The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Bozzoni, Irene +14 more
core +1 more source
CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers [PDF]
BMC Bioinformatics, 2018 Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers.In this study, we present circPrimer, which allows users to search, annotate, and ...
Shanliang Zhong +4 more
openaire +4 more sources
Research Progress of circRNAs in Glioblastoma [PDF]
Frontiers in Cell and Developmental Biology, 2021 Circular RNAs (circRNAs) are a class of single-stranded covalently closed non-coding RNAs without a 5′ cap structure or 3′ terminal poly (A) tail, which are expressed in a variety of tissues and cells with conserved, stable and specific characteristics.
Xu Guo, Haozhe Piao
openaire +4 more sources
Mechanisms of non-coding RNA-modulated alternative splicing in cancer
RNA Biology, 2022 Alternative splicing (AS) is a common and pivotal process for eukaryotic gene expression regulation, which enables a precursor RNA to produce multiple transcript variants with diverse cellular functions.
Xiaolin Wang +6 more
doaj +1 more source
The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies
Translational Research in Urology, 2022 Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade.
Helia Azodian Ghajar +1 more
doaj +1 more source
The functional roles of the circRNA/Wnt axis in cancer
Molecular Cancer, 2022 CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt pathway.
Chen Xue +6 more
semanticscholar +1 more source
陆军军医大学学报, 2022 Objective To explore the effects of the interaction between circular RNA hsa_circ_0000231 and HnRNPK on the proliferation, migration and apoptosis in breast cancer. Methods Microarray analysis was used to investigate the expression profile of circRNAs in
HU Mengting, CHEN Junxia
doaj +1 more source
The Recent Research Progress of CircRNA in Bladder Cancer
Annals of Urologic Oncology, 2023 Bladder cancer is a major public health problem in the world, and is one of the most common malignant tumors in the genito-urinary system. Due to its high incidence and mortality, it remains a serious threat to human health.
Shuo Liu, Xin-liang Xu
doaj +1 more source
Bioinformatics Advances, 2023 ABSTRACTMotivationCircular RNAs (circRNAs) are long non-coding RNAs (lncRNAs) often associated with diseases and considered potential biomarkers for diagnosis and treatment. Among other functions, circRNAs have been shown to act as microRNA (miRNA) sponges, preventing the role of miRNAs that repress their targets.
Markus Hoffmann +10 more
openaire +4 more sources
Translation role of circRNAs in cancers [PDF]
Journal of Clinical Laboratory Analysis, 2021 AbstractCircular RNAs (circRNAs) constitute a class of covalently closed RNA molecules. With the continuous advancement of high‐throughput sequencing technology and bioinformatics tools, many circRNAs have been identified in various human tissues and cell lines.
Yaqin Lu +4 more
openaire +3 more sources