Results 81 to 90 of about 45,661 (289)

Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data

Nucleic Acids Res., 2020
An updated Lnc2Cancer 3.0 (http://www.bio-bigdata.net/lnc2cancer or http://bio-bigdata.hrbmu.edu.cn/lnc2cancer) database, which includes comprehensive data on experimentally supported long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) associated
Yue Gao, Shipeng Shang, Shuang Guo, Xin Li, Hanxiao Zhou, Hongjia Liu, Yue Sun, Junwei Wang, Peng Wang, Hui Zhi, Xia Li, Shangwei Ning, Yunpeng Zhang   +12 more
semanticscholar   +1 more source

Nanopore sequencing of brain-derived full-length circRNAs reveals circRNA-specific exon usage, intron retention and microexons

Nature Communications, 2021
Circular RNA (circRNA) is a class of covalently joined non-coding RNAs with functional roles in a wide variety of cellular processes. Their composition shows extensive overlap with exons found in linear mRNAs making it difficult to delineate their ...
K. Rahimi, M. Venø, D. Dupont, J. Kjems
semanticscholar   +1 more source

Circulating cell-free nucleic acids: characteristics and applications [PDF]

, 2018
K
Biró, Orsolya, Nagy, Bálint, Pös, Ondrej, Szemes, Tomas   +3 more
core   +1 more source

Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function (Review)

Molecular Medicine Reports, 2022
Circular RNA (circRNA) molecules are noncoding RNAs with unique circular covalently closed structures that contribute to gene expression regulation, protein translation and act as microRNA sponges. circRNAs also have important roles in human disease, particularly tumorigenesis and antitumor processes.
Zhang, Chunlei, Cui, Han, Huang, Chuang, Kong, Feiyan, Yang, Qi, Miao, Pengcheng, Cao, Zhigang, Zhang, Weijun, Chang, Dehui   +8 more
openaire   +2 more sources

Construction of a circRNA-Mediated ceRNA Network Reveals Novel Biomarkers for Aortic Dissection

International Journal of General Medicine, 2022
De-Bin Liu,1,* You-Fu He,2– 4,* Gui-Jian Chen,1 Hua Huang,1 Xu-Ling Xie,1 Wan-Jun Lin,1 Zhi-Jian Peng1 1Department of Cardiology, The Second People’s Hospital of Shantou, Shantou, Guangdong Province, People’s Republic of China; 2Department of ...
Liu DB, He YF, Chen GJ, Huang H, Xie XL, Lin WJ, Peng ZJ   +6 more
doaj  

Acfs: accurate circRNA identification and quantification from RNA-Seq data [PDF]

, 2016
Circular RNAs (circRNAs) are a group of single-stranded RNAs in closed circular form. They are splicing-generated, widely expressed in various tissues and have functional implications in development and diseases.
Conrad, Tim O. F., You, Xintian
core   +1 more source

The roles of miRNA, lncRNA and circRNA in the development of osteoporosis

Biological Research, 2020
Osteoporosis is a common metabolic bone disease, influenced by genetic and environmental factors, that increases bone fragility and fracture risk and, therefore, has a serious adverse effect on the quality of life of patients.
Yang Yang, Yujiao Wang, Wang Fang, Linhui Yuan, Guo Ziqi, Zhichen Wei, Wang Zirui, Shengwang Wang   +7 more
semanticscholar   +1 more source

CircRNAs and Fusion-circRNAs in cancer: New players in an old game

Cellular Signalling, 2020
Circular RNAs (circRNAs) are generated from 'back-splicing' events. Their circular structure makes them stable in cells and body fluids. These entities are involved in several human diseases including cancer, as they affect the expression of genes promoting proliferation, invasion, apoptosis, and angiogenesis.
Grazia Visci, Doron Tolomeo, Antonio Agostini, Debora Traversa, Gemma Macchia, Clelia Tiziana Storlazzi   +5 more
openaire   +4 more sources

Exosomal CircRNAs in Circulation Serve as Diagnostic Biomarkers for Acute Myocardial Infarction

Frontiers in Bioscience-Landmark
Background: The diagnostic potential of circular RNAs (circRNAs) in circulating exosomes for acute myocardial infarction (AMI) is not well understood, despite existing research indicating their role in cardiovascular diseases. This study aimed to clarify
Xiaoyan Liu, Yeping Zhang, Wen Yuan, Ruijuan Han, Jiuchang Zhong, Xinchun Yang, Meili Zheng, Boqia Xie   +7 more
doaj   +1 more source

Research Progress on CircRNA in Liquid Biopsy of Gastric Cancer

Zhongliu Fangzhi Yanjiu, 2021
Gastric cancer has become a major public health problem in China because of its high prevalence. CircRNA could stably exist in various human body fluids, providing the innate advantage for the liquid biopsy, which makes it a research hotspot in the field
ZHU Hao, JIA Jianchao, YU Lan
doaj   +1 more source