Results 21 to 30 of about 44,285 (229)

Opportunities and challenges of circulating biomarkers in neuroblastoma [PDF]

open access: yesOpen Biology, 2019
Molecular analysis of nucleic acid and protein biomarkers is becoming increasingly common in paediatric oncology for diagnosis, risk stratification and molecularly targeted therapeutics. However, many current and emerging biomarkers are based on analysis
Ricky M. Trigg   +2 more
doaj   +1 more source

Clinical applications of liquid biopsy in HPV-negative and HPV-positive head and neck squamous cell carcinoma: advances and challenges

open access: yesExploration of Targeted Anti-tumor Therapy, 2022
Head and neck squamous cell carcinomas (HNSCCs) represent the most common epithelial tumors that arise from mucosa of the oral cavity, pharynx, and larynx.
Mariana Chantre-Justino   +2 more
doaj   +1 more source

Liquid biopsy for early detection and therapeutic monitoring of hepatocellular carcinoma [PDF]

open access: yesJournal of Liver Cancer, 2022
Advances in our knowledge of the molecular characteristics of hepatocellular carcinoma (HCC) have enabled significant progress in the detection and therapeutic prediction of HCC.
Eun-Ji Choi, Young-Joon Kim
doaj   +1 more source

Promises and Challenges of Predictive Blood Biomarkers for Locally Advanced Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy

open access: yesCells, 2023
The treatment of locally advanced rectal cancer (LARC) requires a multimodal approach combining neoadjuvant radiotherapy or chemoradiotherapy (CRT) and surgery.
Joao Victor Machado Carvalho   +3 more
doaj   +1 more source

Liquid biopsies for liquid tumors: emerging potential of circulating free nucleic acid evaluation for the management of hematologic malignancies

open access: yesCancer Biology & Medicine, 2016
Circulating free nucleic acids; cell free DNA and circulating micro-RNA, are found in the plasma of patients with hematologic and solid malignancies at levels higher than that of healthy individuals.
Jay Hocking   +3 more
doaj   +1 more source

Hydatidiform mole diagnostics using circulating gestational trophoblasts isolated from maternal blood

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background In gestational trophoblastic disease, the prognosis is related to the genetic constitution. In some cases, taking a biopsy is contraindicated. Methods In a pregnant woman, ultrasound scanning suggested hydatidiform mole.
Lone Sunde   +7 more
doaj   +1 more source

Using cell-free DNA for HCC surveillance and prognosisKey points

open access: yesJHEP Reports, 2021
Summary: Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer. Its incidence is rising faster than any other cancer in the United States and it remains one of the leading causes of cancer-related deaths worldwide. While advances
Nguyen H. Tran   +2 more
doaj   +1 more source

Cell-free Fetal Nucleic Acid Identifier Markers in Maternal Circulation

open access: yesAdvanced Biomedical Research, 2017
From the discovery of cell-free fetal (cff)-DNA in 1997 so far, many studies have been performed on various aspects of cff-nucleic acid. It is undoubted that currently, invasive prenatal diagnosis progresses to the noninvasive test. However, there are many problems.
Mahboubeh Ramezanzadeh   +2 more
openaire   +3 more sources

Advances in Electrochemical Biosensor Technologies for the Detection of Nucleic Acid Breast Cancer Biomarkers

open access: yesSensors, 2023
Breast cancer is the second leading cause of cancer deaths in women worldwide; therefore, there is an increased need for the discovery, development, optimization, and quantification of diagnostic biomarkers that can improve the disease diagnosis ...
Ana-Maria Chiorcea-Paquim
doaj   +1 more source

Circulating biomarkers to monitor cancer progression and treatment

open access: yesComputational and Structural Biotechnology Journal, 2016
Tumor heterogeneity is a major challenge and the root cause of resistance to treatment. Still, the standard diagnostic approach relies on the analysis of a single tumor sample from a local or metastatic site that is obtained at a given time point. Due to
Suthee Rapisuwon   +2 more
doaj   +1 more source

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