Results 31 to 40 of about 76,398 (257)
Biomolecules, 2018 Escherichia coli strains may be beneficial or pathogenic. Many E. coli strains that cause human disease, especially those responsible for bacteremia and sepsis, express virulence factors that impart resistance to the complement system.
Steven G. Biesecker +3 more
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Deficient Classical Complement Pathway Activity in Newborn Sera [PDF]
Pediatric Research, 1983 Summary: The bactericidal activity of 20 maternal-neonatal paired sera was assessed employing a clinical type la, group B streptococcal isolate, strain 515, known to be opsonized by the classical complement pathway in a non-antibody dependent fashion.
M S, Edwards +4 more
openaire +2 more sources
Frontiers in Immunology, 2016 Aspergillus fumigatus infections are associated with a high mortality rate for immunocompromised patients. The complement system is considered to be important in protection against this fungus, yet the course of activation is unclear.
Anne Rosbjerg +5 more
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BMC Complementary Medicine and Therapies, 2022 Introduction Disseminated intravascular coagulation (DIC) is a syndrome characterized by coagulopathy, microthrombus, and multiple organ failure. The complement system in DIC is overactivated, and the functions of complement and coagulation pathways are ...
Qi-Yun Zhang +7 more
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Frontiers in Immunology, 2021 The impairment of the alternative complement pathway contributes to rare kidney diseases such as atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G).
Aleksandra Urban +15 more
doaj +1 more source
Carbamylation of immunoglobulin abrogates activation of the classical complement pathway [PDF]
European Journal of Immunology, 2014 Post‐translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory conditions through myeloperoxidase‐dependent cyanate (CNO−) formation.
Koro, Catalin +12 more
openaire +7 more sources
Nature Communications, 2016 C1q is known to initiate the activation of the complement classical pathway. Here, the authors show the C1q is expressed in the tumour microenvironment and can promote cancer cell migration and adhesion in a complement activation-independent manner.
Roberta Bulla +9 more
doaj +1 more source
Echinococcus multilocularis Calreticulin Interferes with C1q-Mediated Complement Activation
Tropical Medicine and Infectious Disease, 2023 As a zoonotic disease caused by Echinococcus multilocularis larvae, alveolar echinococcosis (AE) is one of the most severe forms of parasitic infection. Over a long evolutional process E.
Siqi Xian +8 more
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Activation of the classical pathway of complement by rheumatoid factors [PDF]
Arthritis & Rheumatism, 1982 AbstractA simple, sensitive solid‐phase radioimmunoassay to quantitate the activation of the classical pathway of complement by rheumatoid factor (RF) is described. RF (purified, in serum or synovial fluid) was bound to reduced and alkylated IgG adsorbed to polyvinyl chloride microtiter plates and reacted with diluted normal human serum (complement ...
Umesh K. Sabharwal +5 more
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Marine Drugs, 2022 The widespread resistance to antibiotics in pathogenic bacteria makes the development of a new generation of antimicrobials an urgent task. The development of new antibiotics must be accompanied by a comprehensive study of all of their biological ...
Ilia A. Krenev +8 more
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