Results 121 to 130 of about 78,811 (306)

Active dry granular flows: rheology and rigidity transitions

, 2016
The constitutive relations of a dense granular flow composed of self-propelling frictional hard particles are investigated by means of DEM numerical simulations.
Andreotti, Bruno, Claudin, Philippe, Clement, Eric, Peshkov, Anton   +3 more
core   +3 more sources

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

A two‐sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy

Epilepsia Open, EarlyView.
Abstract Objective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis. Methods Publicly accessible summary statistics on epilepsy were obtained from FinnGen and the International League Against Epilepsy Consortium.
Huaiyu Sun, Di Ma, Wuqiong Zhang, Shuai Hou, Zhiqing Chen, Xuewei Li, Hongmei Meng, Daguang Zhang   +7 more
wiley   +1 more source

Scale separation in granular packings: stress plateaus and fluctuations

, 2006
It is demonstrated, by numerical simulations of a 2D assembly of polydisperse disks, that there exists a range (plateau) of coarse graining scales for which the stress tensor field in a granular solid is nearly resolution independent, thereby enabling an
A. P. F. Atman, C. Goldenberg, C. Truesdell, G. Combe, G. K. Batchelor, I. Goldhirsch, M. Born, P. Claudin, P. A. Cundall   +8 more
core   +3 more sources

Desulfovibrio‐Hydrogen Sulfide Mediates Capsaicin‐Induced Oxidative Stress and Gut Inflammation via TXNIP/NLRP3 Pathway

Food Bioengineering, EarlyView.
ABSTRACT The intake of capsaicin can disrupt the gut microecology and impact health, yet its underlying mechanism is not fully elucidated. This study, by establishing capsaicin‐induced human microbiota‐associated (HMA) mouse models revealed the molecular mechanism by which capsaicin perturbs the gut microbiota and metabolites, leading to intestinal ...
Liangliang Zhu, Xiangru Feng, Xiaoxuan Lu, Geng Han, Jiaqi Zou, Zhaoyang Dong, Ting Luo, Jiayang Jin, Mengyao Zhao, Xiaoguo Ji, Liming Zhao   +10 more
wiley   +1 more source

Field evidence for the upwind velocity shift at the crest of low dunes

, 2013
Wind topographically forced by hills and sand dunes accelerates on the upwind (stoss) slopes and reduces on the downwind (lee) slopes. This secondary wind regime, however, possesses a subtle effect, reported here for the first time from field ...
A Fourrière, B Andreotti, B Andreotti, B Andreotti, B. Andreotti, C McKenna-Neuman, C Narteau, D Poggi, DP Zilker, DP Zilker, DS Henn, F Engelund, F Engelund, G Sauermann, G. F. S. Wiggs, GFS Wiggs, GFS Wiggs, H Elbelrhiti, HS Yoon, I Livingstone, IJ Walker, J Buckles, J Fredsøe, JCR Hunt, JE Stout, JF Kennedy, JH Boxel van, JJ Finnigan, K Kroy, K Kroy, KA Frederick, KJ Richards, KJ Richards, KW Ayotte, M Benalla, M Colombini, MC Baddock, MV Salvetti, N Lancaster, O Durán, O Durán, P Cherukat, P Claudin, P Hersen, P. Claudin, PA Taylor, PS Jackson, RI Sykes, SE Belcher, SR McLean, V Angelis de, W Gong, W Gong, WS Weng   +53 more
core   +1 more source

Local Rheology Relation with Variable Yield Stress Ratio across Dry, Wet, Dense, and Dilute Granular Flows

, 2019
Dry, wet, dense, and dilute granular flows have been previously considered fundamentally different and thus described by distinct, and in many cases incompatible, rheologies.
de Klerk, David N., Durán, Orencio, Govender, Indresan, Pähtz, Thomas, Trulsson, Martin   +4 more
core   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Gross Intrahepatic Mass Formation Predicts the Primary Site of Perihilar Cholangiocarcinoma Based on Molecular Pathologic Studies

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Intrahepatic cholangiocarcinoma (iCCA) and extrahepatic cholangiocarcinoma (eCCA) are clinically and genetically distinct. However, the classification of perihilar cholangiocarcinoma (phCCA) with an intrahepatic tumor mass remains unclear.
Yuki Masuda, Naoto Kubota, Ryo Takemura, Yasuhito Arai, Yuta Abe, Osamu Itano, Minoru Esaki, Tatsuhiro Shibata, Yuko Kitagawa, Hidenori Ojima   +9 more
wiley   +1 more source