Results 71 to 80 of about 80,593 (229)
I am pretty sure that I don’t have to spend a single word to talk about the role played by tight junctions in biological processes and in keeping alive the cellular bases of life ! But I am sure as well that the readers should appreciate at least some sentences about this relatively new entry (Claudins have been discovered in 1998) in the world of the ...
openaire +3 more sources
Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh +11 more
wiley +1 more source
La Revolución Pictórica de Nuestro Tiempo.
La Revolución Pictórica de Nuestro Tiempo.
Fernando Claudín
doaj
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley +1 more source
The Expression of the Claudin Family of Proteins in Colorectal Cancer
Claudins (CLDN1–CLDN24) are a family of tight junction proteins whose dysregulation has been implicated in tumorigeneses of many cancer types. In colorectal cancer (CRC), CLDN1, CLDN2, CLDN4, and CLDN18 have been shown to either be upregulated or ...
Kristin E. Cox +5 more
doaj +1 more source
Localization of Claudin‐3 and Claudin‐4 within the Small Intestine of newborn piglets
Piglets must acquire passive immunity through colostrum within hours after birth to survive. How colostral macromolecules traverse the small intestinal epithelium may include nonselective pinocytosis and paracellular transport through tight junction ...
Brodie Deluco +3 more
doaj +1 more source
Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications. [PDF]
Trop2 is a transmembrane glycoprotein encoded by the Tacstd2 gene. It is an intracellular calcium signal transducer that is differentially expressed in many cancers. It signals cells for self-renewal, proliferation, invasion, and survival.
Bonavida, Benjamin, Shvartsur, Anna
core +2 more sources
A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu +8 more
wiley +1 more source
OBJETIVO: Analizar los resultados del Programa de Medicamentos Antirretrovirales Gratuitos del Programa de VIH/SIDA de la Ciudad de México (PVSCM) en la población afectada del Distrito Federal.
Carmen Soler Claudín
doaj
Direct numerical simulations of aeolian sand ripples
Aeolian sand beds exhibit regular patterns of ripples resulting from the interaction between topography and sediment transport. Their characteristics have been so far related to reptation transport caused by the impacts on the ground of grains entrained ...
Andreotti, Bruno +2 more
core +1 more source

