Results 81 to 90 of about 79,602 (359)
Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies. [PDF]
, 2016 Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the tight junction protein claudin-2 by cytokines is hypothesized to contribute to the ...
Glen Hughes +19 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu +5 more
wiley +1 more source
Salud Pública de México, 2009 OBJETIVO: Analizar los resultados del Programa de Medicamentos Antirretrovirales Gratuitos del Programa de VIH/SIDA de la Ciudad de México (PVSCM) en la población afectada del Distrito Federal.
Carmen Soler Claudín
doaj
Oncology Letters, 2020 The incidence of esophageal adenocarcinoma (EAC) has rapidly increased, particularly in the Western world. Despite improvements in perioperative treatments, the overall survival of patients remains low.
Valeska Moentenich +10 more
semanticscholar +1 more source
Claudins and gastric carcinogenesis
Experimental Biology and Medicine, 2013 Gastric carcinoma arises from aberrant growth of normal gastric mucosa. There is increasing evidence that claudins (CLDNs) may play a critical role in the significant steps of gastric tumorigenesis, from metaplasia to metastasis. The CLDN family which consists of at least 27 member proteins is known to mediate selective permeability in cellular tight ...
Omid, Iravani +4 more
openaire +2 more sources
Advanced Materials, EarlyView.Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma +15 more
wiley +1 more source
La Revolución Pictórica de Nuestro Tiempo.
La Universidad, 2018 La Revolución Pictórica de Nuestro Tiempo.
Fernando Claudín
doaj
The Expression of the Claudin Family of Proteins in Colorectal Cancer
BiomoleculesClaudins (CLDN1–CLDN24) are a family of tight junction proteins whose dysregulation has been implicated in tumorigeneses of many cancer types. In colorectal cancer (CRC), CLDN1, CLDN2, CLDN4, and CLDN18 have been shown to either be upregulated or ...
Kristin E. Cox +5 more
doaj +1 more source
Localization of Claudin‐3 and Claudin‐4 within the Small Intestine of newborn piglets
Physiological Reports, 2021 Piglets must acquire passive immunity through colostrum within hours after birth to survive. How colostral macromolecules traverse the small intestinal epithelium may include nonselective pinocytosis and paracellular transport through tight junction ...
Brodie Deluco +3 more
doaj +1 more source
Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease.
Journal of Clinical Investigation, 2020 The major risk factor for kidney stone disease is idiopathic hypercalciuria. Recent evidence implicates a role for defective calcium reabsorption in the renal proximal tubule.
Joshua N. Curry +15 more
semanticscholar +1 more source