Results 11 to 20 of about 14,885 (290)
Claudins in lung diseases [PDF]
Respiratory Research, 2011 Tight junctions are the most apically localized part of the epithelial junctional complex. They regulate the permeability and polarity of cell layers and create compartments in cell membranes. Claudins are structural molecules of tight junctions.
Soini Ylermi
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European Journal of Histochemistry, 2012 I am pretty sure that I don’t have to spend a single word to talk about the role played by tight junctions in biological processes and in keeping alive the cellular bases of life !
Carlo Alberto Redi
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Claudins: Beyond Tight Junctions in Human IBD and Murine Models
Frontiers in Pharmacology, 2021 Claudins are transmembrane proteins constituting one of three tight junction protein families. In patients with inflammatory bowel disease (IBD), disease activity–dependent changes in expression of certain claudins have been noted, thus making certain ...
Snježana Čužić +25 more
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Structure and function of claudins [PDF]
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2008 Claudins are tetraspan transmembrane proteins of tight junctions. They determine the barrier properties of this type of cell-cell contact existing between the plasma membranes of two neighbouring cells, such as occurring in endothelia or epithelia. Claudins can completely tighten the paracellular cleft for solutes, and they can form paracellular ion ...
Krause, Gerd +5 more
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Claudins in the Renal Collecting Duct [PDF]
International Journal of Molecular Sciences, 2019 The renal collecting duct fine-tunes urinary composition, and thereby, coordinates key physiological processes, such as volume/blood pressure regulation, electrolyte-free water reabsorption, and acid-base homeostasis. The collecting duct epithelium is comprised of a tight epithelial barrier resulting in a strict separation of intraluminal urine and the
Janna Leiz, Kai M. Schmidt-Ott
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Structure-forward targeting of claudins with synthetic binders. [PDF]
FEBS LettClaudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Vecchio AJ.
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Expression and Targeted Application of Claudins Family in Hepatobiliary and Pancreatic Diseases [PDF]
Journal of Hepatocellular CarcinomaFangqian Du,1,* Yuwei Xie,1,* Shengze Wu,1 Mengling Ji,2 Bingzi Dong,3 Chengzhan Zhu1 1Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 2Department of Surgery,
Du F, Xie Y, Wu S, Ji M, Dong B, Zhu C
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Genome Biology, 2009 The claudin multigene family encodes tetraspan membrane proteins that are crucial structural and functional components of tight junctions, which have important roles in regulating paracellular permeability and maintaining cell polarity in epithelial and endothelial cell sheets.
Lal-Nag, Madhu, Morin, Patrice J
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Annual Review of Physiology, 2013 Claudins are tight junction membrane proteins that regulate paracellular permeability of renal epithelia to small ions, solutes, and water. Claudins interact within the cell membrane and between neighboring cells to form tight junction strands and constitute both the paracellular barrier and the pore.
Jianghui, Hou +2 more
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Claudins in ovarian cancer: emerging biomarkers and therapeutic targets. [PDF]
Tissue BarriersTight junctions (TJ) comprise protein complexes that help with the movement of ions and molecules through the paracellular pathway, thus maintaining both epithelial and endothelial integrity.
Therachiyil L, Bhat AA, Uddin S.
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