Results 11 to 20 of about 20,650 (306)
European Journal of Histochemistry, 2012 I am pretty sure that I don’t have to spend a single word to talk about the role played by tight junctions in biological processes and in keeping alive the cellular bases of life !
Carlo Alberto Redi
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Claudins in the Renal Collecting Duct [PDF]
International Journal of Molecular Sciences, 2019 The renal collecting duct fine-tunes urinary composition, and thereby, coordinates key physiological processes, such as volume/blood pressure regulation, electrolyte-free water reabsorption, and acid-base homeostasis.
Leiz, Janna, Schmitt-Ott, Kai M.
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Genome Biology, 2009 The claudin multigene family encodes tetraspan membrane proteins that are crucial structural and functional components of tight junctions, which have important roles in regulating paracellular permeability and maintaining cell polarity in epithelial and endothelial cell sheets.
Lal-Nag, Madhu, Morin, Patrice J
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Annual Review of Physiology, 2013 Claudins are tight junction membrane proteins that regulate paracellular permeability of renal epithelia to small ions, solutes, and water. Claudins interact within the cell membrane and between neighboring cells to form tight junction strands and constitute both the paracellular barrier and the pore.
Jianghui, Hou +2 more
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Cells, 2022 Claudins are a family of integral membrane proteins that enable epithelial cell/cell interactions by localizing to and driving the formation of tight junctions.
Chinemerem P. Ogbu +2 more
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SUMOylation of claudin‐2 [PDF]
Annals of the New York Academy of Sciences, 2012 The C‐terminal cytoplasmic tails of claudins are likely sites for interaction with proteins that regulate their function. We performed a yeast two‐hybrid screen with the tail of human claudin‐2 against a human kidney cDNA library and identified interactions with the PDZ3 domain of ZO‐2 as well as ubiquitin‐conjugating enzyme E2I (SUMO ligase‐1) and E3 ...
Christina M, Van Itallie +2 more
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The role and mechanism of claudins in cancer
Frontiers in Oncology, 2022 Claudins are a tetraspan membrane protein multigene family that plays a structural and functional role in constructing tight junctions. Claudins perform crucial roles in maintaining cell polarity in epithelial and endothelial cell sheets and controlling ...
De-Wen Wang +10 more
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Role of Stress on Driving the Intestinal Paracellular Permeability
Current Issues in Molecular Biology, 2023 The gut epithelium is a polarized monolayer that exhibits apical and basolateral membrane surfaces. Monolayer cell components are joined side by side via protein complexes known as tight junction proteins (TJPs), expressed at the most apical extreme of ...
Daniel Efrain Molotla-Torres +3 more
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Developmental expression of claudins in the mammary gland [PDF]
, 2017 Claudins are a large family of membrane proteins whose classic function is to regulate the permeability of tight junctions in epithelia. They are tetraspanins, with four alpha-helices crossing the membrane, two extracellular loops, a short cytoplasmic N ...
Baumgartner, Heidi K. +8 more
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The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression [PDF]
, 2009 The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects.
Bracarense, Ana-Paula +8 more
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