Results 231 to 240 of about 20,415 (303)

Ion permeability profiles of renal paracellular channel-forming claudins. [PDF]

open access: yesActa Physiol (Oxf)
Pouyiourou I   +5 more
europepmc   +1 more source

The Diagnostic Promise of Serum S100B Protein in Pregnancy‐Related Hypertension: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Hypertensive disorders of pregnancy (HDP) are a major cause of illness and death for mothers and babies worldwide. Their number is rising due to older maternal age, obesity, and other health problems. Early diagnosis is important. Serum protein S100B, a calcium‐binding protein studied in brain diseases, is now being considered as a ...
Moldir Dossimbetova   +9 more
wiley   +1 more source

Indomethacin Fails to Increase Intestinal Permeability in Healthy Volunteers. [PDF]

open access: yesClin Transl Gastroenterol
Camilleri M   +10 more
europepmc   +1 more source

Therapeutic Galectin‐3 Apheresis Improves Sepsis Outcomes Through Coordinated Neutrophil Modulation and Endothelial Barrier Preservation: A Translational Study

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun   +7 more
wiley   +1 more source

Impaired Intestinal Mucosal Barrier upon Ischemia-Reperfusion: “Patching Holes in the Shield with a Simple Surgical Method” [PDF]

open access: yes, 2015
Fülöp, András   +10 more
core  

Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Within minutes after ischemia onset, deprivation of oxygen and glucose leads to rapid ATP depletion, resulting in failure of Na+/K+‐ATPase activity and membrane depolarization. This ionic imbalance promotes uncontrolled synaptic release of glutamate and excessive activation of postsynaptic NMDA and AMPA receptors.
Meibiao Zhang   +4 more
wiley   +1 more source

Blood–Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This graphical abstract illustrates how blood–brain barrier‐targeted nanomedicine integrates diverse nanocarrier platforms with mechanism‐based therapeutic strategies to overcome delivery barriers in ischemic stroke, enabling targeted modulation of oxidative stress, inflammation, excitotoxicity, and neuronal survival.
Yanan He   +10 more
wiley   +1 more source

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