Ion permeability profiles of renal paracellular channel-forming claudins. [PDF]
Pouyiourou I +5 more
europepmc +1 more source
The Diagnostic Promise of Serum S100B Protein in Pregnancy‐Related Hypertension: A Narrative Review
ABSTRACT Background Hypertensive disorders of pregnancy (HDP) are a major cause of illness and death for mothers and babies worldwide. Their number is rising due to older maternal age, obesity, and other health problems. Early diagnosis is important. Serum protein S100B, a calcium‐binding protein studied in brain diseases, is now being considered as a ...
Moldir Dossimbetova +9 more
wiley +1 more source
Indomethacin Fails to Increase Intestinal Permeability in Healthy Volunteers. [PDF]
Camilleri M +10 more
europepmc +1 more source
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun +7 more
wiley +1 more source
Structural and functional comparative analysis of porcine and human salivary glands: a narrative review for translational research. [PDF]
Vanelli L +3 more
europepmc +1 more source
Impaired Intestinal Mucosal Barrier upon Ischemia-Reperfusion: “Patching Holes in the Shield with a Simple Surgical Method” [PDF]
Fülöp, András +10 more
core
Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management
Within minutes after ischemia onset, deprivation of oxygen and glucose leads to rapid ATP depletion, resulting in failure of Na+/K+‐ATPase activity and membrane depolarization. This ionic imbalance promotes uncontrolled synaptic release of glutamate and excessive activation of postsynaptic NMDA and AMPA receptors.
Meibiao Zhang +4 more
wiley +1 more source
CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review). [PDF]
Lai X, Yan Y, Sun L, Lei Z, Yang Y.
europepmc +1 more source
Blood–Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems
This graphical abstract illustrates how blood–brain barrier‐targeted nanomedicine integrates diverse nanocarrier platforms with mechanism‐based therapeutic strategies to overcome delivery barriers in ischemic stroke, enabling targeted modulation of oxidative stress, inflammation, excitotoxicity, and neuronal survival.
Yanan He +10 more
wiley +1 more source

