Exploring claudin proteins: from sequence motifs to their impact on tight junction-mediated signaling pathways. [PDF]
Bao L, Yang S, Zhao W, Zuo Y.
europepmc +1 more source
EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto +8 more
wiley +1 more source
Research progress on the role of Claudin family proteins in mediating blood-brain barrier selective permeability in tumor metastasis. [PDF]
Wei D +7 more
europepmc +1 more source
CLDN18 (43‐14A) is expressed in most gastric type adenocarcinomas and a much smaller proportion of HPV‐associated adenocarcinomas. Expression of CLDN18.2 mRNA but not CLDN18.1 mRNA is confirmed in both gastric type adenocarcinomas and HPV‐associated adenocarcinomas.
Nobuko Yasutake +12 more
wiley +1 more source
Essential amino acids preserve intestinal barrier integrity <i>via</i> mitochondrial protection in obesity and gut inflammation. [PDF]
Spataro L +11 more
europepmc +1 more source
Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg +3 more
wiley +1 more source
Microbiota-Derived Regulation of AhR and VDR Signaling in Intestinal Inflammation: Protective Roles of Prebiotics, Probiotics, and Postbiotics. [PDF]
Huang FC.
europepmc +1 more source
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh +6 more
wiley +1 more source
Whispering Through the Barrier: Signaling Interfaces for Peripheral Regulation of Brain Function in Obesity. [PDF]
Kaya MZ, Stranahan AM.
europepmc +1 more source

