Results 61 to 70 of about 84,756 (126)

Mtail-Seq For Pan2/3, Caf1A/B (Cnot7/8) Kd Hela Samples (Internal Id: Ms121)

, 2018
mTAIL-seq, MiSeq run (internal ID: ms121) spkN, spk8, spk16, spk32, spk64, spk118, spk128 spike-ins NC2 (siCont), 232 (siPAN2/3), 783 (siCAF1a/b or siCNOT7/8) samples This dataset contains cluster intensities of fluorescence signals that are repacked as an HDF5 formatted file.
Park, Joha, Yi, Hyerim, Kim, V. Narry
openaire   +1 more source

Spleen transcriptomics reveals breed-specific mechanisms of Salmonella resistance under heat stress in chickens

Poultry Science
Heat stress and Salmonella infection are two major challenges threatening poultry health and productivity. Native breeds generally show stronger resistance than commercial lines, but the molecular mechanisms underlying this advantage remain unclear. This
Yaping Wang, Qiao Wang, Zixuan Wang, Xiang Li, Mohamed Shafey Elsharkawy, Yangqing Lu, Guiping Zhao, Changbo Ou   +7 more
doaj   +1 more source

Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach [PDF]

Protein & Cell, 2015
Bai, Yuwei, Tashiro, Shinya, Nagatoishi, Satoru, Suzuki, Toru, Yan, Dongke, Liu, Ruihua, Tsumoto, Kouhei, Bartlam, Mark, Yamamoto, Tadashi   +8 more
openaire   +2 more sources

Μελέτες στη βιολογική σημασία της ανθρώπινης αποαδενυλάσης CNOT7

, 2010
Η ακριβής γονιδιακή έκφραση απαιτεί συνεχή έλεγχο των επιπέδων του mRNA. Η αποικοδόμηση του mRNA αποτελεί ρυθμιστικό στοιχείο της γονίδιακής έκφρασης. Στα κύτταρα των θηλαστικών το κύριο μονοπάτι αποικοδόμησης ξεκινά με αποαδενυλίωση, την αφαίρεση δηλαδή των πολύ(Α) ουρών από το 3' άκρο ενός ώριμου mRNA.
openaire   +1 more source

M2 Macrophage Classification of Colorectal Cancer Reveals Intrinsic Connections with Metabolism Reprogramming and Clinical Characteristics

Pharmacogenomics and Personalized Medicine
Fengxing Huang,1,2,* Youwei Wang,1,2,* Yu Shao,1,2,* Runan Zhang,1,2 Mengting Li,1,2 Lan Liu,1,2,* Qiu Zhao1,2,* 1Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People’s Republic of China; 2Hubei
Huang F, Wang Y, Shao Y, Zhang R, Li M, Liu L, Zhao Q   +6 more
doaj  

CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex

CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex
The CCR4-NOT deadenylase complex is a major post-transcriptional regulator of eukaryotic gene expression. CNOT7 and CNOT8 are both vertebrate homologs of the yeast CCR4-NOT catalytic subunit Caf1. They are highly similar and are sometimes considered redundant, but Cnot7 and Cnot8 knockout mice exhibit different phenotypes, implying distinct ...
openaire  

Functional Proximity across an mRNA. [PDF]

Biochemistry
Hatfield BM, Weidmann CA, McCutchin CA, Irving PS, Nelson IM, Felder S, Weeks KM.   +6 more
europepmc   +1 more source

Mobilization of Dormant Cnot7 mRNA Promotes Deadenylation of Maternal Transcripts During Mouse Oocyte Maturation1

Biology of Reproduction, 2015
Jun Ma, Yusuke Fukuda, Richard M. Schultz   +2 more
openaire   +1 more source

Is Staphylococcus epidermidis Involved in the Etiopathogenesis of Pitted Keratolysis? [PDF]

Acta Derm Venereol
Veraldi S, Schianchi R, Aromolo IF, Nazzaro G.   +3 more
europepmc   +1 more source

A next-generation dual guide CRISPR system for genetic interaction library screening. [PDF]

Nat Commun
Burgold T, Karakoc E, Gonçalves E, Barrio-Hernandez I, Dwane L, Silva R, Souster E, Sharma M, Beck A, Koh GCC, Zalmas LP, Garnett MJ, Bassett AR.   +12 more
europepmc   +1 more source