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The Complement System of Agnathans [PDF]
Frontiers in Immunology, 2018 Agnathans (lamprey and hagfish) are a group of primitive jawless fish. Jawed vertebrates possess adaptive immunity including immunoglobulins, while agnathans lack immunoglobulins but have alternative adaptive immunity in which variable lymphocyte ...
Misao Matsushita
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British Journal of Anaesthesia, 1979 The complement system (C) is composed of group of plasma proteins which under certain conditions react with each other sequentially, resulting in the formation of highly specialized proteases. By their action multimolecular complexes are assembled, and when these events occur on the surface of some cells, the membrane function is impaired and the cell ...
Bryan Williams
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The complement system in lipid-mediated pathologies [PDF]
Frontiers in ImmunologyThe complement system, a coordinator and facilitator of the innate immune response, plays an essential role in maintaining host homeostasis. It promotes clearance of pathogen- and danger-associated molecular patterns, regulates adaptive immunity, and can
Lejla Alic +2 more
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Complement System Deficiencies in Elite Athletes [PDF]
Sports Medicine - OpenBackground Although regular physical activity improves immune competency and reduces the prevalence of inflammatory diseases, strenuous training in elite athletes is associated with an increased susceptibility to infectious complications.
Libor Vítek +3 more
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COVID-19, Pre-Eclampsia, and Complement System
Frontiers in Immunology, 2021 COVID-19 is characterized by virus-induced injury leading to multi-organ failure, together with inflammatory reaction, endothelial cell (EC) injury, and prothrombotic coagulopathy with thrombotic events.
Chiara Agostinis +7 more
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Terminal Complement Pathway Deficiency in an Adult Patient with Meningococcal Sepsis
Case Reports in Immunology, 2022 The complement system is an essential part of our innate immune system. Three enzymatic activation pathways are described, all converging into a common terminal pathway which causes lysis of the target cell.
F. Staels +8 more
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Current Biology, 1998 Work in the authors' laboratories is supported by grants from the Arthritis and Rheumatism Council and the Wellcome Trust.
Marina Botto +2 more
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The Complement System in Kidney Transplantation
Cells, 2023 Kidney transplantation is the therapy of choice for patients who suffer from end-stage renal diseases. Despite improvements in surgical techniques and immunosuppressive treatments, long-term graft survival remains a challenge.
Donata Santarsiero, Sistiana Aiello
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The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
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Proprotein Convertases and the Complement System
Frontiers in Immunology, 2022 Proteins destined for secretion - after removal of the signal sequence - often undergo further proteolytic processing by proprotein convertases (PCs).
József Dobó +3 more
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