Results 11 to 20 of about 1,832,799 (306)

Antimicrobial Peptide Arenicin-1 Derivative Ar-1-(C/A) as Complement System Modulator

open access: yesMarine Drugs, 2020
Antimicrobial peptides (AMPs) are not only cytotoxic towards host pathogens or cancer cells but also are able to act as immunomodulators. It was shown that some human and non-human AMPs can interact with complement proteins and thereby modulate ...
Ilia A. Krenev   +11 more
doaj   +1 more source

The complement system and autoimmune diseases

open access: yesChronic Diseases and Translational Medicine, 2022
The complement system plays a key role in the pathogenesis of autoimmune diseases, which usually injures the kidney. More and more studies have shown the pathogenic role and indicated that abnormal activation of the complement system was highly involved ...
Changhao Jia, Ying Tan, Minghui Zhao
doaj   +1 more source

The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System

open access: yesBiomolecules, 2022
The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi   +5 more
doaj   +1 more source

Complement activation and protein adsorption by carbon nanotubes [PDF]

open access: yes, 2006
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel   +5 more
core   +2 more sources

The Complement System of Agnathans

open access: yesFrontiers in Immunology, 2018
Agnathans (lamprey and hagfish) are a group of primitive jawless fish. Jawed vertebrates possess adaptive immunity including immunoglobulins, while agnathans lack immunoglobulins but have alternative adaptive immunity in which variable lymphocyte ...
Misao Matsushita
doaj   +1 more source

Detection and characterisation of Complement protein activity in bovine milk by bactericidal sequestration assay [PDF]

open access: yes, 2015
Susan Maye is in receipt of a Teagasc Walsh Fellowship. Financial support by the Department of Agriculture, Food and the Marine is gratefully acknowledged.Copyright © Proprietors of Journal of Dairy Research 2015 (Institute of Food Research and the ...
Fitzgerald, Gerald F   +3 more
core   +1 more source

On the Modulation Equations and Stability of Periodic GKdV Waves via Bloch Decompositions [PDF]

open access: yes, 2010
In this paper, we complement recent results of Bronski and Johnson and of Johnson and Zumbrun concerning the modulational stability of spatially periodic traveling wave solutions of the generalized Korteweg-de Vries equation. In this previous work it was
Bampi   +33 more
core   +1 more source

The complement system

open access: yesCell and Tissue Research, 2010
The complement system consists of a tightly regulated network of proteins that play an important role in host defense and inflammation. Complement activation results in opsonization of pathogens and their removal by phagocytes, as well as cell lysis.
Sarma, J. Vidya, Ward, Peter A.
openaire   +3 more sources

Quantitative multiplex profiling of the complement system to diagnose complement‐mediated diseases

open access: yesClinical & Translational Immunology, 2020
Objectives Complement deficiencies are difficult to diagnose because of the variability of symptoms and the complexity of the diagnostic process. Here, we applied a novel ‘complementomics’ approach to study the impact of various complement deficiencies ...
Esther Willems   +23 more
doaj   +1 more source

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial

open access: yesRespiratory Research, 2022
Background The efficacy and safety of complement inhibition in COVID-19 patients is unclear. Methods A multicenter randomized controlled, open-label trial.
Elisabeth De Leeuw   +27 more
doaj   +1 more source

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