Results 11 to 20 of about 24,198,541 (380)
British Journal of Anaesthesia, 1979 The complement system (C) is composed of group of plasma proteins which under certain conditions react with each other sequentially, resulting in the formation of highly specialized proteases. By their action multimolecular complexes are assembled, and when these events occur on the surface of some cells, the membrane function is impaired and the cell ...
Bryan Williams
+9 more sources
International Journal of Molecular Sciences, 2023 The crosstalk among the complement system, immune cells, and mediators of inflammation provides an efficient mechanism to protect the organism against infections and support the repair of damaged tissues. Alterations in this complex machinery play a role
F. Lasorsa +10 more
semanticscholar +1 more source
COVID-19, Pre-Eclampsia, and Complement System
Frontiers in Immunology, 2021 COVID-19 is characterized by virus-induced injury leading to multi-organ failure, together with inflammatory reaction, endothelial cell (EC) injury, and prothrombotic coagulopathy with thrombotic events.
Chiara Agostinis +7 more
doaj +1 more source
The complement system in age-related macular degeneration
Cellular and Molecular Life Sciences, 2021 Age-related macular degeneration (AMD) is a chronic and progressive degenerative disease of the retina, which culminates in blindness and affects mainly the elderly population.
A. Armento, M. Ueffing, Simon J. Clark
semanticscholar +1 more source
Terminal Complement Pathway Deficiency in an Adult Patient with Meningococcal Sepsis
Case Reports in Immunology, 2022 The complement system is an essential part of our innate immune system. Three enzymatic activation pathways are described, all converging into a common terminal pathway which causes lysis of the target cell.
F. Staels +8 more
doaj +1 more source
The Complement System, Aging, and Aging-Related Diseases
International Journal of Molecular Sciences, 2022 The complement system is a part of the immune system and consists of multiple complement components with biological functions such as defense against pathogens and immunomodulation.
Runzi Zheng +5 more
semanticscholar +1 more source
Current Biology, 1998 Work in the authors' laboratories is supported by grants from the Arthritis and Rheumatism Council and the Wellcome Trust.
Marina Botto +2 more
openaire +3 more sources
Streptococcus pneumoniae interactions with the complement system
Frontiers in Cellular and Infection Microbiology, 2022 Host innate and adaptive immunity to infection with Streptococcus pneumoniae is critically dependent on the complement system, demonstrated by the high incidence of invasive S.
Eliza Gil +2 more
semanticscholar +1 more source
The Complement System in Kidney Transplantation
Cells, 2023 Kidney transplantation is the therapy of choice for patients who suffer from end-stage renal diseases. Despite improvements in surgical techniques and immunosuppressive treatments, long-term graft survival remains a challenge.
Donata Santarsiero, Sistiana Aiello
doaj +1 more source
The Complement System in the Central Nervous System: From Neurodevelopment to Neurodegeneration
Biomolecules, 2022 The functions of the complement system to both innate and adaptive immunity through opsonization, cell lysis, and inflammatory activities are well known.
Ying Chen, J. Chu, R. Chang, G. Wong
semanticscholar +1 more source