A peptide dataset for target analysis of human complement system proteins [PDF]
Data in BriefThe targeted LC-MS/MS method has been widely applied for peptide quantification, offering sensibility, specificity, and reproducibility to the analysis. However, it requires the prior selection of targets, including the construction of a spectral library.
Thais Cristina Tirado +4 more
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Plasmid-encoded toxin of Escherichia coli cleaves complement system proteins and inhibits complement-mediated lysis in vitro [PDF]
Frontiers in Cellular and Infection MicrobiologyPlasmid-encoded toxin (Pet) is an autotransporter protein of the serine protease autotransporters of Enterobacteriaceae (SPATE) family, important in the pathogenicity of Escherichia coli. The pet gene was initially found in the enteroaggregative E. coli (
Gabriel B. Correa +7 more
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Genetic mapping of complement system proteins for islet autoimmunity in children with high risk of T1D [PDF]
Communications BiologyRecent studies have reported the involvement of complement system proteins in the initiation and progression of islet autoimmunity (IA) in the study of Type 1 diabetes (T1D).
Xiaowei Hu +10 more
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Инфекция и иммунитет, 2022 The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova +1 more
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Interference of the Zika Virus E-Protein With the Membrane Attack Complex of the Complement System [PDF]
Frontiers in Immunology, 2020 The complement system has developed different strategies to clear infections by several effector mechanisms, such as opsonization, which supports phagocytosis, attracting immune cells by C3 and C5 cleavage products, or direct killing of pathogens by the ...
Zahra Malekshahi +5 more
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Complement proteins associated with circulatory and glomerular IgA-containing immune complexes in patients with IgA nephropathy [PDF]
Scientific ReportsIgA nephropathy (IgAN) is characterized by glomerular deposits of IgA-containing immune complexes (IgA-ICs), which are suspected to originate from circulation. However, the composition of these ICs is not fully understood.
Yudai Tsuji +10 more
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Complement System Proteins in the Human Aqueous Humor and Their Association with Primary Open-Angle Glaucoma. [PDF]
J Pers Med, 2023 Vashishtha A +11 more
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Low serum complement level is associated with higher mortality in tuberculous meningitis: a retrospective cohort study [PDF]
Encephalitis, 2023 Purpose We evaluated the associations between serum complement levels and tuberculous meningitis (TBM), bacterial meningitis (BM), and viral meningitis (VM), as well as the association between serum complement levels and mortality in TBM.
Hansol Im +7 more
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Comprehensive review of membranoproliferative glomerulonephritis: spotlighting the latest advances in revised classification and treatment [PDF]
Childhood Kidney Diseases, 2023 Membranoproliferative glomerulonephritis (MPGN) is a complex group of renal diseases characterized by a specific pattern of glomerular injury that includes thickening of the capillary wall and mesangial expansion, leading to a heterogeneous group of ...
Jeong Yeon Kim
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The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
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