Results 61 to 70 of about 11,073 (199)
Syntaxin 3b is a t-SNARE specific for ribbon synapses of the retina. [PDF]
, 2008 Previous studies have demonstrated that ribbon synapses in the retina do not contain the t-SNARE (target-soluble N-ethylmaleimide-sensitive factor attachment protein receptor) syntaxin 1A that is found in conventional synapses of the nervous system.
Curtis, Leigh B +5 more
core +1 more source
Protein phase separation hotspots at the presynapse
Open Biology, 2022 Fundamental discoveries have shaped our molecular understanding of presynaptic processes, such as neurotransmitter release, active zone organization and mechanisms of synaptic vesicle (SV) recycling.
Janin Lautenschläger
doaj +1 more source
, 2004 Number of Pages: 6Integrative BiologyGeological ...
Ernst, Carl H., Stuart, James N.
core +1 more source
The accessory helix of complexin functions by stabilizing central helix secondary structure
eLife, 2014 The presynaptic protein complexin (CPX) is a critical regulator of synaptic vesicle fusion, but the mechanisms underlying its regulatory effects are not well understood. Its highly conserved central helix (CH) directly binds the ternary SNARE complex and
Daniel T Radoff +5 more
doaj +1 more source
In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties.
, 2019 Regulated exocytosis of synaptic vesicles is substantially faster than of endocrine dense core vesicles despite similar molecular machineries. The reasons for this difference are unknown and could be due to different regulatory proteins, different ...
Castle, J. +10 more
core +1 more source
Environmental Perturbations that Cause Structural Changes in the SNARE Protein SNAP-25 [PDF]
, 1992 Digitalitzat per ...
Hansen, Jaron J. +6 more
core +1 more source
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION Alzheimer's disease (AD) study participants may present with cognitive impairment who do not have brain amyloid deposits (Aβ−). Identifying predictive biomarkers for non‐amyloid‐related CI may provide better screening tests for trials seeking only CI Aβ+ participants and new therapy targets.
Richard C. Mohs +11 more
wiley +1 more source
A Reassessment of the Urban Context of the Republican Baths (VIII 5, 36) [PDF]
, 2018 Das Foro Triangolare wird gewöhnlich als Ort eines athletischmilitärischen Komplexes im späthellenistischen Samnitischen Pompeji identifiziert. Benennung (gymnasium, campus, palaestra der vereiia) und Ausdehnung sind zwar umstritten, aber die ...
Trümper, Monika
core +1 more source
FASEB BioAdvances, Volume 8, Issue 1, January 2026.GABA‐producing Lactococcus lactis protects against experimental autoimmune encephalomyelitis (EAE) in a mouse source‐dependent manner. The study focuses on the therapeutic potential of genetically engineered gamma‐aminobutyric acid (GABA)‐overproducing Lactococcus lactis (P8s‐GAD L. lactis) in the EAE model.
Kristina Hill +11 more
wiley +1 more source
A mechanism for exocytotic arrest by the Complexin C-terminus
eLife, 2018 ComplexinII (CpxII) inhibits non-synchronized vesicle fusion, but the underlying mechanisms have remained unclear. Here, we provide evidence that the far C-terminal domain (CTD) of CpxII interferes with SNARE assembly, thereby arresting tonic exocytosis.
Mazen Makke +9 more
doaj +1 more source