Results 81 to 90 of about 11,073 (199)
Modelling probabilistic cache representativeness in the presence of arbitrary access patterns [PDF]
, 2016 Measurement-Based Probabilistic Timing Analysis (MBPTA) is a promising powerful industry-friendly method to derive worst-case execution time (WCET) estimates as needed for critical real-time embedded systems.
Abella Ferrer, Jaume +2 more
core +1 more source
Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways
PROTEOMICS, Volume 25, Issue 21-22, Page 214-229, November 2025.ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu +3 more
wiley +1 more source
Complexing additives to reduce the immiscible phase formed in the hybrid ZnBr2 flow battery [PDF]
, 2017 The zinc-bromine redox flow battery (RFB) is one of a very few commercially viable RFB energy storage system capable of integration with intermittent renewable energy sources to deliver improved energy management.
Berlouis, L. +4 more
core +1 more source
Presynaptic quantal size enhancement counteracts post‐tetanic release depression
The Journal of Physiology, Volume 603, Issue 20, Page 6051-6071, October 15, 2025.Abstract figure legend Sustained high‐frequency stimulation decreases the number of synaptic vesicles that fuse per action potential at the Drosophila neuromuscular junction. However, the postsynaptic response remains largely unchanged. An increased postsynaptic response to individual vesicles, likely driven by an increase in vesicle size resulting ...
Anu G. Nair +5 more
wiley +1 more source
Functional Roles of Complexin 3 and Complexin 4 at Mouse Photoreceptor Ribbon Synapses [PDF]
The Journal of Neuroscience, 2016 Complexins (Cplxs) are SNARE complex regulators controlling the speed and Ca(2+) sensitivity of SNARE-mediated synaptic vesicle fusion. We have shown previously that photoreceptor ribbon synapses in mouse retina are equipped with Cplx3 and Cplx4 and that lack of both Cplxs perturbs photoreceptor ribbon synaptic function; however, Cplx3/4 function in ...
Norbert Babai +8 more
openaire +4 more sources
Flood of June 9, 1957, at Perry, Florida [PDF]
, 1958 Floods occurred on streams in the vicinity of Perry, Taylor County, Florida, on June 9, 1957, as a result of heavy rains from atropical disturbance. Serious flooding occurred in Perry along Spring and Pimple creeks as outlined by the shaded area in ...
Musgrove, R. H.
core
The Ins and Outs of miRNA-Mediated Gene Silencing during Neuronal Synaptic Plasticity [PDF]
, 2016 Neuronal connections through specialized junctions, known as synapses, create circuits that underlie brain function. Synaptic plasticity, i.e., structural and functional changes to synapses, occurs in response to neuronal activity and is a critical ...
Hanley, Jonathan, Rajgor, Dipen
core +3 more sources
The Journal of Physiology, Volume 603, Issue 20, Page 6207-6227, October 15, 2025.Abstract figure legend Monomeric and multimeric α‐synuclein were purified from HEK cells and delivered to lamprey reticulospinal (RS) synapses via axonal microinjection, followed by stimulation (20 Hz, 5 min). Ultrastructural analysis showed that both α‐synuclein species impaired intracellular vesicle trafficking, leading to synaptic vesicle loss and ...
Cristina Román‐Vendrell +5 more
wiley +1 more source
Structurally and functionally unique complexins at retinal ribbon synapses [PDF]
The Journal of Cell Biology, 2005 Ribbon synapses in retinal sensory neurons maintain large pools of readily releasable synaptic vesicles. This allows them to release several hundreds of vesicles per second at every presynaptic release site. The molecular components that cause this high transmitter release efficiency of ribbon synapses are unknown.
Reim, K. +7 more
openaire +5 more sources
The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis [PDF]
Nature, 2017 Synaptotagmin, complexin, and neuronal SNARE (soluble N-ethylmaleimide sensitive factor attachment protein receptor) proteins mediate evoked synchronous neurotransmitter release, but the molecular mechanisms mediating the cooperation between these molecules remain unclear.
Qiangjun, Zhou +6 more
openaire +2 more sources