Results 111 to 120 of about 2,164 (171)

Prey Shifts Drive Venom Evolution in Cone Snails. [PDF]

Mol Biol Evol
Koch TL, Robinson SD, Salcedo PF, Chase K, Biggs J, Fedosov AE, Yandell M, Olivera BM, Safavi-Hemami H.   +8 more
europepmc   +1 more source

Redox-Active Conopeptide Li520 Has Evolved to Catalyze Oxidative Folding of Conotoxins. [PDF]

ACS Omega
Dhannura S, Shekh S, Dhurjad P, Dolle A, Kakkat S, Vishwajyothi, Vijayasarathy M, Sonti R, Gowd KH.   +8 more
europepmc   +1 more source

Molecular Insights into the Marine Gastropod <i>Olivancillaria urceus</i>: Transcriptomic and Proteopeptidomic Approaches Reveal Polypeptides with Putative Therapeutic Potential. [PDF]

Int J Mol Sci
Barros GM, Gama LF, Mello FR, Corrêa CN, Fiametti LO, Montenegro H, Ottoni CA, Castro LM.   +7 more
europepmc   +1 more source

Profiling the Paralytic Effects and Lethality of Cone Snail Venom Toxins Using Nanofractionation Analytics with <i>In Vivo</i> Zebrafish Larvae Assays. [PDF]

Toxins (Basel)
Kool J, Arrahman A, Xu H, Liu J, Lewis RJ, Tudorache C, Cardoso FC.   +6 more
europepmc   +1 more source

Stapling Cysteine[2,4] Disulfide Bond of α-Conotoxin LsIA and Its Potential in Target Delivery. [PDF]

Mar Drugs
Sun X, Hu J, Ren M, Chang H, Zhangsun D, Zhang B, Dong S.   +6 more
europepmc   +1 more source

Single Amino Acid Substitution in Loop1 Switches the Selectivity of α-Conotoxin RegIIA towards the α7 Nicotinic Acetylcholine Receptor. [PDF]

Mar Drugs
Yu J, Xie J, Ma Y, Wei P, Zhang P, Tang Z, Zhu X, Zhangsun D, Luo S.   +8 more
europepmc   +1 more source

Sustained Release of αO-Conotoxin GeXIVA[1,2] via Hydrogel Microneedle Patch for Chronic Neuropathic Pain Management. [PDF]

Mar Drugs
He R, Li M, Li W, Li W, Xiao S, Cao Q, Wang H, Zhangsun D, Luo S.   +8 more
europepmc   +1 more source

Exploring the Pain-Relieving Potential: Unveiling Antinociceptive Properties in Animal Venoms and Toxins. [PDF]

Toxins (Basel)
Angstmam DG, Jeronimo BC, Cavalcante JDS, Pereira AFM, Villarreal CF, Pimenta DC, Ferreira Junior RS.   +6 more
europepmc   +1 more source

Nicotinic acetylcholine receptors in pain modulation. [PDF]

Front Pharmacol
Cheng J, Chang J, Li S.
europepmc   +1 more source

Conotoxins: Chemistry and Biology [PDF]

Chemical Reviews, 2019
The venom of the marine predatory cone snails (genus Conus) has evolved for prey capture and defense, providing the basis for survival and rapid diversification of the now estimated 750+ species. A typical Conus venom contains hundreds to thousands of bioactive peptides known as conotoxins.
Ai-Hua Jin, Markus Muttenthaler, Sebastien Dutertre, S.W.A. Himaya, Quentin Kaas, David J. Craik, Richard J. Lewis, Paul F. Alewood   +7 more
openaire   +4 more sources